Terzhinan

General characteristics. Structure:

Active agents: тернидазол 200 mg; Neomycinum sulfate of 100 mg (65 000 ME); nystatin of 100 000 ME; Prednisolonum metasulfosodium benzoate of 4.7 mg that corresponds to the content of Prednisolonum of 3 mg

Excipients: starch wheat - 264 mg, lactoses monohydrate - q.s. to 1.2 g, silicon dioxide colloid - 6 mg, magnesium stearate - 10 mg, sodium carboxymethylstarch - 48 mg.

Pharmacological properties:

Pharmacodynamics. Ternidazol has trikhomonatsidny effect, and also is active concerning anaerobic bacteria, in particular гарднерелл.
Neomycinum sulfate — an aminoglikozidny antibiotic of a broad spectrum of activity.
Nystatin — an antifungal half-yen antibiotic, is active concerning sort Candida mushrooms; Prednisolonum — GKS, possesses antiinflammatory action.
The structure of ekstsipiyent of tablets allows to provide integrity of a mucous membrane of a vagina and physiological level рН.

The pharmacokinetics was not studied.

Indications to use:

Treatment at the vaginitis caused by microorganisms, sensitive to drug, including:

• the bacterial vaginitis caused by banal piogenic microflora;
• the nonspecific vaginitis which is followed by desquamative allocations;
• vagina trichomoniasis;
• the vaginitis caused by sort Candida mushrooms;
• the vaginitis caused by multi-infection (trichomonads, a mephitic gangrene and drozhzhepodobny mushrooms).

Route of administration and doses:

The drug Terzhinan is administered deeply in a vagina on 1–2 tablet a day. The average duration of a course of treatment — 10 days. In cases of the confirmed mycosis treatment duration — 20 days. Therapy is not stopped during periods. Before introduction to a vagina the tablet needs to be taken in water during 20–30 pages. After introduction of a tablet it is necessary to lie within 15 min.

Features of use:

Simultaneous treatment of the sexual partner is necessary for prevention of threat of repeated infection.
Some drugs with nystatin used intravaginalno can damage latex contraceptives.
Considering possible insignificant absorption of Prednisolonum, it is necessary to take into account that at use of system GKS observation of the corresponding specialists in the presence at the patient of osteoporosis, AG or heart failure and also existing or which are available in the anamnesis of serious emotional frustration, a diabetes mellitus, tuberculosis, glaucoma, the myopathy caused by use of GKS, a liver failure, epilepsy, a round ulcer, a hypothyroidism, recently postponed myocardial infarction is necessary.
Children. Do not apply.
Use during pregnancy or feeding by a breast. Use is possible under control of the doctor, after individual consultation.
Ability to influence speed of response at control of vehicles or work with other mechanisms. Does not influence.

Side effects:

Allergic reactions to active ingredients of drug, including urticaria, rash on skin; reactions in an injection site — burning, pain, an itch, feeling of a pricking or irritation; erosion, hypersensitivity.
System effects: at topical administration insignificant absorption of components of drug is possible. At emergence of system effects from GKS delay of healing of wounds and cracks, a mucosal atrophy is possible.

Interaction with other medicines:

It is not revealed.

Contraindications:

Hypersensitivity to drug components.

Overdose:

 Due to the insignificant absorption of drug in system blood circulation the overdose is improbable. At overdose strengthening of manifestations of side reactions is possible. In that case it is necessary to cancel drug use.

Treatment: symptomatic.

Storage conditions:

At a temperature not above 25 °C.
To store in the place, unavailable to children.

Issue conditions:

According to the recipe

Packaging:

1 vaginal tablet contains a ternidazol of 200 mg, Neomycinum of sulfate of 100 mg, nystatin of 100000 PIECES and Prednisolonum of metasulfosodium benzoate of 3 mg, and also эксципиент, including oils of a geranium and a carnation to 1,2 g; in packaging of 6 and 10 pieces.