Tykveol

General characteristics. Structure:

Active ingredient: 450 mg of oil of seeds of pumpkin.

The complex drug containing biologically active agents received from pumpkin seeds.

Pharmacological properties:

Pharmacodynamics. High content of tokoferol (alpha, beta, gamma, sigma isomers) and carotinoids has the expressed antioxidant effect oppressing processes of peroxide oxidation of lipids in biological membranes.

Essential phospholipids have hepatoprotective effect, recovery of a cellular membrane of hepatocytes is promoted, by its structures and functions.

Essential fatty acids participate in lipidic exchange, in regulation of exchange of cholesterol and triglycerides, in metabolism of arachidonic acid (as biochemical predecessor of prostaglandins).

Total set of pharmacological properties of biologically active agents in drug Tykveol defines his antiinflammatory and cytoprotective action at topical administration.

Tykveol improves a functional condition of biliary tract, changing chemical composition of bile, possesses easy cholagogue action, reduces the inflammatory phenomena in an epithelium of bile-excreting system.

Tykveol, having anti-androgenic properties, reduces proliferation of cells of a prostate, normalizes its function due to improvement of microcirculation and antiinflammatory action.

Pharmacokinetics. Effect of drug Tykveol is cumulative action of its components therefore carrying out kinetic observations is not possible; everything together components cannot be tracked by means of markers or bioresearches. For the same reason it is impossible to find also metabolites of drug.

Indications to use:

— cirrhosis;

— chronic hepatitis;

— fatty degeneration of a liver;

— infectious hepatitis;

— toxic damages of a liver (medicines, industrial poisons, alcohol);

— cholecystitis (not calculous);

— cholestasia;

— dyskinesia of biliary tract;

— gastritis;

— colitis, coloenteritis (noninfectious genesis);

— hemorrhoids;

— atherosclerosis;

— prostatitis;

— benign hyperplasia of a prostate.

Route of administration and doses:

Inside appoint drug in 30 min. prior to food on 1 teaspoon of oil of 3-4 times/days within 1-3 months or on 4 capsules of 3 times/days in time or after food.

Features of use:

Use at pregnancy and feeding by a breast. Clinical data on efficiency and safety of use of Tykveol at pregnancy and in the period of a lactation are absent.

In case of development of side effects it is necessary to lower a drug dose.

Tykveol apply both in the form of monotherapy, and as a part of complex therapy.

Drug is compatible to any foodstuff.

At inflammatory and degenerative processes of a mucous membrane of upper parts of a GIT recommend to accept Tykveol in the form of oil, it is necessary to avoid administration of drug in the form of capsules.

Use in pediatrics. Clinical data on efficiency and safety of use of drug for children are absent.

Duration of therapy has to be not less than 2-3 weeks - at gastrointestinal diseases, 4 weeks - at pathology of a prostate, 6-8 weeks - at liver diseases.

Side effects:

From the alimentary system: seldom - dyspepsia, diarrhea.

Others: allergic reactions.

Interaction with other medicines:

Clinically significant interaction of Tykveol with other medicines it is not established.

Contraindications:

— hypersensitivity to drug components.

Overdose:

Symptoms: diarrhea.

Treatment: it is necessary to lower a drug dose.

Storage conditions:

Capsules and oil for intake should be stored in protected from light, the place, unavailable to children, at a temperature from -10 °C to +25 °C. Suppositories rectal should be stored in dry, protected from light, the place, unavailable to children, at a temperature not above 5 °C. A period of validity - 2 years.

Issue conditions:

Without recipe

Packaging:

50 pieces - banks polymeric (1) - packs cardboard.
84 pieces - banks polymeric (1) - packs cardboard.
20 pieces - banks polymeric (1) - packs cardboard.
30 pieces - banks polymeric (1) - packs cardboard.
90 pieces - banks polymeric (1) - packs cardboard.
180 pieces - banks polymeric (1) - packs cardboard.
20 pieces - planimetric strip packagings (1) - packs cardboard.
10 pieces - planimetric strip packagings (1) - packs cardboard.