Askovit

General characteristics. Structure:

Active agent: ascorbic acid - 1000,00 mg.

Excipients: sodium bicarbonate, sorbitol, citric acid, polyethyleneglycol, saccharin, aspartame, aromatic additive "lemon" or "orange", E-104 dye (quinolinic yellow), E-101 (Riboflavinum) – for lemon, E-110 dye (sunset-yellow) – for orange.

Pharmacological properties:

Ascorbic acid plays an important role in regulation of oxidation-reduction processes, carbohydrate metabolism, coagulability of blood, fabric regeneration; participates in synthesis of corticosteroids, collagen and procollagen; normalizes permeability of capillaries, reduces the need for B1, B2, A, E vitamins, folic acid, pantothenic acid. Has the antiagregantny and expressed antiokidantny properties. Activates proteolytic enzymes, participates in exchange of aromatic amino acids, pigments and cholesterol, promotes accumulation in a glycogen liver. Due to activation of respiratory enzymes in a liver strengthens its disintoxication and belkovoobrazovatelny functions, increases synthesis of a prothrombin. Improves bile secretion, recovers vneshnesekretorny function of a pancreas and incretory – thyroid. Promotes phagocytosis, increases body resistance to infections.

Indications to use:

Prevention and treatment hypo - and vitamin C avitaminosis.

As supportive application: hemorrhagic diathesis, nasal, pulmonary, uterine and other bleedings, acute radial illness; overdose of anticoagulants, inertly healing wounds and fractures of bones. Drug is appointed at the raised exercise and intellectual stresses, during recovery after a serious and long illness.

Route of administration and doses:

To accept inside, after food, previously having dissolved a tablet in half of glass of water. In the preventive purposes - 500 mg/days, with the medical purpose of 1000 mg/days.

Features of use:

Products rich with ascorbic acid: citrus, greens, vegetables (pepper, broccoli, headed cabbage, tomatoes, potatoes). At storage of products (including long freezing, drying, a pickles, pickling), cooking (especially in copper ware), crushing of vegetables and fruit in salads, preparation of puree there is a partial destruction of ascorbic acid (at temperature processing - to 30-50%).
In connection with a promoting effect of ascorbic acid on synthesis of corticosteroid hormones it is necessary to monitor function of adrenal glands and arterial pressure.
At prolonged use of high doses oppression of function of the insulyarny device of a pancreas therefore in the course of its treatment it is regularly necessary to control is possible.
At patients with the increased content of iron in an organism it is necessary to apply ascorbic acid in the minimum doses.
Purpose of ascorbic acid to patients with quickly proliferating and intensively metastasizing tumors can aggravate the course of process.

Ascorbic acid as a reducer can distort results of various laboratory tests (content in blood of glucose, bilirubin, activity of "hepatic" transaminases and LDG).

Side effects:

Allergic reactions. Irritation of a mucous membrane of a GIT, arterial hypertension, disbolism, oppression of function of the insulyarny device of a pancreas, thrombocytosis, thrombogenesis.

Interaction with other medicines:

Increases concentration in blood of benzylpenicillin and tetracyclines. Reduces anti-coagulative effect of derivatives of coumarin. Improves absorption in intestines of iron preparations. Drugs of a quinolinic row, Calcii chloridum, salicylates, corticosteroids at prolonged use exhaust vitamin C reserves. Reduces efficiency of heparin and indirect anticoagulants. Acetylsalicylic acid, oral contraceptives, fresh juice and alkaline drink reduce absorption and assimilation. Increases risk of development of a crystalluria at treatment by salicylates and sulfanilamida of short action, slows down removal by kidneys of acids, reduces concentration in blood of oral contraceptives.

Contraindications:

Hypersensitivity to drug components, the increased coagulability of blood, thrombophlebitises, tendency to fibrinferments, a diabetes mellitus.

Overdose:

Data on overdose are not provided.

Storage conditions:

In the dry, protected from light place at a temperature not above 25 °C. To store in the place, unavailable to children.

Issue conditions:

Without recipe

Packaging:

On 10, 12, 14 tablets in a plastic case with a plastic stopper. On 2, 4, 6, 10 tablets in the PVC/Al blister. On 2, 4, 6, 8, 10 tablets in Al/Al strip.
On 1 case in a cardboard pack or a pack envelope with the device for suspension together with the application instruction; on 1, 2, 3, 4, 5 blisters or strips in a cardboard pack together with the application instruction.