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medicalmeds.eu Medicines The antimicrobic means applied in ophthalmology. SODIUM SULFACETAMIDE

SODIUM SULFACETAMIDE

Препарат СУЛЬФАЦИЛ НАТРИЯ. ЧАО "Биофарма" Украина


Producer: CIAO Biofarm Ukraine

Code of automatic telephone exchange: S01A B04

Release form: Liquid dosage forms. Drops are eye.

Indications to use: Conjunctivitis. Keratitis. Blepharitis. Purulent helcoma. Blennorey.


General characteristics. Structure:

Active ingredient: 1 ml of solution contains 300 mg of Sodium sulfacetamidum;
 
excipients: sodium metabisulphite, 1M hydroxide sodium solution, water for injections.




Pharmacological properties:

Pharmacodynamics. Antimicrobic means of group of streptocides. Drug is effective at streptococcal, gonococcal, pneumococcal and collibacillary infections. Works bacteriostatically. The mechanism of action is connected with competitive antagonism with para-aminobenzoic acid and competitive oppression of a digidropteroatsintetaza that leads to disturbance of synthesis of the tetrahydrofolic acid necessary for synthesis of purines and pyrimidines.
 
Pharmacokinetics. At instillation on a conjunctiva the sulfacetamide of sodium gets into the eye environment where makes the specific antibacterial impact. Works preferential locally, but a part of drug is soaked up through the inflamed conjunctiva and gets to a system blood stream.


Indications to use:

Infectious and inflammatory diseases of eyes which are caused by microflora, sensitive to drug (conjunctivitis, a keratitis, blepharites, purulent helcomas, бленнорея). Gonorrheal diseases of eyes at newborns and adults, prevention of a blennorea at newborns.


Route of administration and doses:

Drug is dug in in the affected eye on 1–2 drops of 3-6 times a day. Course of treatment of 7-10 days. At gonorrheal diseases of eyes: topical treatment (in the form of an instillation of 30% solution a sodium sulfacetamide). For prevention of a blennorea at newborns dig in in eyes on the 2nd drop directly after the birth and on the 2nd drop in 2 hours.


Features of use:

At helcomas powder it the crushed powder (powder) a sulfacetamide of sodium of 5-6 times a day to full epithelization, then pass 30% of aqueous solution to an instillation. During pregnancy and feeding by a breast of sufficient experiment on use there is no drug. Use of a sulfacetamide of sodium for treatment of pregnant women is possible and during a lactation on doctor's orders if the expected medical effect exceeds risk of development of possible side effects.


Side effects:

The taking place burning in eyes, reddening of a conjunctiva.


Interaction with other medicines:

At combined use with novocaine, Dicainum, anaesthesin the bacteriostatic effect decreases; dipheninum, salicylates increase toxicity of a sulfacetamide of sodium; at use from antikoagulyana of indirect action specific activity of the last increases. The sodium sulfacetamide at topical administration is incompatible with silver salts.


Contraindications:

Hypersensitivity to components of drug and other streptocides.


Overdose:

Symptoms. Considerable irritation of a mucous membrane of an eye.

Treatment: in these cases immediately stop administration of drug. In case of need appoint symptomatic therapy.


Storage conditions:

To store in the place protected from light, at a temperature from 8 °Сдо 15 °C. A period of storage – 2 years. After opening of a bottle – 20 days.


Issue conditions:

According to the recipe


Packaging:

On 5 or 10 ml of 30 % of solution in a bottle.



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