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medicalmeds.eu Medicines The means influencing cardiovascular system. Niacin - Darnitsa, solution for and 1% po1 ml No. 10

Niacin - Darnitsa, solution for and 1% po1 ml No. 10

Препарат Кислота никотиновая - Дарница, р-р д/и 1% по1 мл №10. ЗАО "Фармацевтическая фирма "Дарница" Украина


Producer: CJSC Pharmaceutical Firm Darnitsa Ukraine

Code of automatic telephone exchange: C04AC01

Release form: Liquid dosage forms. Solution for injections.

Indications to use: Pellagra. Gipoatsidny gastritis. Hepatitis. Cirrhosis. Atherosclerosis. Neuritis of a facial nerve.


General characteristics. Structure:

Chemical name: 3-pyridine carboxylic acid;
main physical and chemical properties: transparent colourless liquid;
structure: niacin of-10 g;
excipients: Natrii hydrocarbonas, water for injections.




Pharmacological properties:

Acid nikotinovaya-Darnitsa (and niacinamide, close to it) - are prosthetic groups of co-dehydrase I and co-dehydrase II - the enzymes which are transferring hydrogen and carrying out oxidation-reduction processes. The second of enzymes plays a role and in phosphate transportation. Insufficiency of niacin leads to emergence of a pellagra. Acid nikotinovaya-Darnitsa improves exchange of carbohydrates, expands vessels, renders positive effect at heart diseases, a liver, easy forms of diabetes, a peptic ulcer of a stomach and a 12-perstny gut, coloenterites, inertly regenerating ulcers and wounds. Has lipoproteidemichesky activity, at a hypercholesterolemia the indicator lowers cholesterol / phospholipids.


Indications to use:

Acid nikotinovuyu-Darnitsa is appointed as specific means for prevention and treatment of a pellagra, and also applied at pathological processes in digestive tract, in particular at gipoatsidny gastritises, at acute and chronic hepatitises, liver cirrhoses, vasospasms (a brain, kidneys, extremities), atherosclerosis, neuritis of a facial nerve, infectious and other diseases, it is long not healing ulcers and wounds of various localization and genesis.


Route of administration and doses:

Acid nikotinovuyu-Darnitsa is appointed intravenously (intramuscular and subcutaneous injections are painful therefore they in need of such way of introduction use niacinamide or sodium никотинат).
As a vazodilatator at an ischemic stroke intravenously slowly enter 1 ml of 1% of solution.
At a pellagra appoint by the adult parenterally 1 ml of 1% of solution 1-2 times a day for 10-15 days. To children appoint 0,005 - 0,05 g 2 - 3 times a day. At other diseases drug is appointed by the adult for 0,02 - 0,05 (to 0,1 g), to children on 0,005 - 0,03 g by 2 - 3 times a day.
The highest doses for adults intravenously (in the form of sodium salt); one-time - 0,1 g, daily - 0,3 g.


Features of use:

At hypersensitivity to drug (except for use as a vasodilator) it is necessary to appoint niacinamide.
As prolonged use of Acid nikotinovoy-Darnitsa can lead to fatty dystrophy of a liver, for prevention of the last include products rich with methionine in a diet of patients or that is appointed in itself (as well as other lipotropic drugs).


Side effects:

Acid nikotinovaya-Darnitsa, especially at reception on an empty stomach, can cause urticaria, paresthesias, dizziness, feeling of inflow to the head, a dermahemia of the person and an upper half of a trunk. As a rule, the specified effects disappear independently. At bystry intravenous administration arterial pressure can strongly go down.



Contraindications:

Acid nikotinovaya-Darnitsa (intravenous administration) is contraindicated at severe forms of an idiopathic hypertensia and atherosclerosis.



Storage conditions:

To store in the place protected from light. A period of validity - 5 years.


Issue conditions:

According to the recipe


Packaging:

On 1 ml of solution in ampoules No. 10.



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