DE   EN   ES   FR   IT   PT


medicalmeds.eu Medicines Nootropic drugs. Tserepro

Tserepro

Препарат Церепро. ОАО "ВЕРОФАРМ" Россия


Producer: JSC VEROPHARM Russia

Code of automatic telephone exchange: N07AX02

Release form: Liquid dosage forms. Solution for injections.

Indications to use: Hemorrhagic stroke. Ischemic stroke. Consciousness disturbances. Encephalopathy. Dementia.


General characteristics. Structure:

Active agent 250 of mg глицерилфосфорилхолин hydrate (sincaline альфосцерат); excipient - water for injections. Description: solution for intramuscular and intravenous administration: transparent colourless liquid.




Pharmacological properties:

The central holinostimulyator as a part of which 40,5% of metabolic protected sincaline contain (metabolic protection promotes release of sincaline in a brain). At hit in an organism it is split under the influence of enzymes on sincaline and glycerophosphate: sincaline participates in biosynthesis of acetylcholine — one of the main mediators of nervous excitement; glycerophosphate is a predecessor of phospholipids (phosphatidylsincaline) of a neural membrane. Provides synthesis of acetylcholine and phosphatidylsincaline in neyronalny membranes, improves a blood stream and strengthens metabolic processes in the central nervous system, activates a reticular formation. Increases the linear speed of a blood-groove on the party of traumatic damage of a brain, contributes to normalization of spatio-temporal characteristics of spontaneous bioelectric activity of a brain; exerts positive impact on cognitive and behavioural reactions of patients with vascular diseases of a brain. Improves functions of a brain, influencing pathogenetic factors of an involutional psychoorganic syndrome, changes phospholipidic structure of membranes of neurons and reduces cholinergic activity. Dozozavisimo stimulates allocation of acetylcholine; participating in phosphatidylsincaline synthesis (membrane phospholipid), improves synoptic transfer, plasticity of neyronalny membranes, function of receptors. Does not exert impact on a reproductive cycle and does not possess teratogenic and mutagen action. The pharmacokinetics Absorption — 88%, easily gets through a blood-brain barrier (at oral administration concentration in a brain — 45% of that in plasma). It is removed preferential easy, in the form of carbon dioxide (85%), and also kidneys and through intestines (15%).


Indications to use:

 

- The acute and recovery periods of a severe craniocereberal injury and ischemic stroke, the recovery period of a hemorrhagic stroke proceeding with focal polusharny symptomatology or symptoms of defeat of a brainstem;
- a psychoorganic syndrome against the background of degenerative and involutional changes of a brain; chronic insufficiency of cerebral circulation;
- cognitive frustration (disturbances of cogitative function, memory, confusion of consciousness, a disorientation, decrease in motivation, initiative and ability of concentration of attention) including at dementia and encephalopathy;
- senile pseudo-melancholy.


Route of administration and doses:

At acute states: intramusculary or intravenously (slowly) on 1,0 g (1 ampoule) a day for 10–15 days, then pass to reception of capsules inside 0,8 g (2 capsules) in the morning and 0,4 g (1 capsule) in the afternoon within 6 months. At chronicities: inside on 0,4 g (1 capsule) 3 times a day, are preferable to food. Duration of treatment makes 3–6 months.


Features of use:

When developing nausea after administration of drug it is necessary to reduce a dose. Tserepro does not exert impact on speed of psychomotor reactions.


Side effects:

Allergic reactions, nausea (owing to dopaminergic activation).


Interaction with other medicines:

 It is not revealed.


Contraindications:

Hypersensitivity, pregnancy, breastfeeding.


Overdose:

Symptoms: dispeptic frustration. Treatment: gastric lavage, reception of absorbent carbon, symptomatic therapy.


Storage conditions:

Period of validity Solution for intramuscular and intravenous administration — 2 years. Not to use after the term specified on packaging. List B. Solution: in protected from light and the place, unavailable to children, at a temperature of 25 °C.


Issue conditions:

According to the recipe


Packaging:

Solution for intravenous and intramuscular administration of 250 mg/ml in ampoules on 4 ml. On 3, 5 or 10 ampoules together with  the application instruction in a box from a cardboard or on 3 or 5 ampoules in a blister strip packaging.



Similar drugs

Препарат Делецит. ОАО "ВЕРОФАРМ" Россия

Deletsit

Nootropic means.



Препарат Церетон®. ОАО "ВЕРОФАРМ" Россия

Церетон®

Nootropic means.



Препарат Глиатилин. ОАО "ВЕРОФАРМ" Россия

Gliatilin

Nootropic drugs.



Препарат Холитилин®. ОАО "ВЕРОФАРМ" Россия

Холитилин®

Nootropic means.



Препарат Церепро. ОАО "ВЕРОФАРМ" Россия

Tserepro

Nootropic drugs.



Препарат Делецит 400. ОАО "ВЕРОФАРМ" Россия

Deletsit 40

Nootropic means.



Препарат Церетон®. ОАО "ВЕРОФАРМ" Россия

Церетон®

Nootropic means.



Препарат Делецит 1000. ОАО "ВЕРОФАРМ" Россия

Deletsit 100

Nootropic means.



Препарат Церепро. ОАО "ВЕРОФАРМ" Россия

Tserepro

Nootropic means.





  • Сайт детского здоровья