Odeston

General characteristics. Structure:

Active ingredient: 200 mg of a gimekromon.

Excipients: potato starch – 45 mg, gelatin – 3 mg, sodium lauryl sulfate – 1 mg, magnesium stearate – 1 mg.

Cholagogue drug.

Pharmacological properties:

Pharmacodynamics. Cholagogue drug. Increases education and biliation. Also the arterial pressure (AP) has the selection spasmolytic effect concerning bilious channels and Oddi's sphincter (does not reduce a peristaltics of the digestive tract (DT)). Reduces stagnation of bile, prevents cholesterol crystallization and by that development of a cholelithiasis.

Pharmacokinetics. At intake it is easily soaked up from a digestive tract, poorly contacts proteins of plasma. The maximum concentration in blood serum is reached in 2-3 hours. The elimination half-life makes about 1 hour. Gimekromon is brought by kidneys (about 93% in the form of a glyukuronat, 1,4% - sulphonate, 0,3% - in not changed look).

Indications to use:

Dyskinesia of biliary tract and Oddi's sphincter on hyperkinetic type, not calculous chronic cholecystitis, a cholangitis, a cholelithiasis; a state after operative measures on a gall bladder and bilious ways. A loss of appetite, nausea, locks, vomiting (against the background of bile hyposecretion).

Route of administration and doses:

Inside, in 30 minutes prior to food; the adult – on 200-400 mg three times a day. Daily dose of 1200 mg. Course of treatment 2 weeks. In case of the admission of reception of a dose it is necessary to accept drug as soon as possible or if time of the following reception comes, not to accept the passed dose. It is not necessary to accept a double dose at once.

Features of use:

Use at pregnancy and a lactation. There are no data on safety of use of a gimekromon during pregnancy and a lactation. Odeston's appointment to pregnant women and in the period of a lactation is admissible only when the potential advantage for mother exceeds potential risk for a fruit and the child.

Drug does not exert impact on ability to manage vehicles and to be engaged in other potentially dangerous types of activity demanding the increased concentration of attention and speed of psychomotor reactions.

Medicines cannot be thrown out in the sewerage or in house containers for waste. How to utilize unused drug, learn from the druggist. These actions will help to protect the environment.

Side effects:

Allergic reactions; diarrhea, meteorism, abdominal pain, expression of a mucous membrane of a GIT, headache.

Interaction with other medicines:

Morphine weakens action of a gimekromon.

At joint reception to Metoclopramidum there is a weakening of effect of both drugs.

Strengthens effects of indirect anticoagulants.

Contraindications:

Hypersensitivity. Impassability of biliary tract, renal/liver failure, ulcer colitis, disease Krone, peptic ulcer of a stomach and 12-perstny gut, hemophilia. Children's age up to 18 years.

Overdose:

There are no data concerning cases of overdose of medicine at people.

Storage conditions:

At a temperature not above 25 °C. To store in the place, unavailable to children. Period of validity 3 years.

Issue conditions:

Without recipe

Packaging:

Tablets on 200 mg. On 50 tablets in the PVC/ave blister. On 1 blister together with the application instruction in a cardboard pack. On 10 tablets in the PVC/ave blister. On 5 blisters together with the application instruction in a cardboard pack.