Venoplant

General characteristics. Structure:

Active agent: 263,2 mg of a horse-chestnut (Aesculus hippocastanum L.) fruits extract of dry (4,5Yo5,5:1), 50 mg the maintenance of triterpenovy glycosides in terms of эсцин anhydrous. Extragent – ethanol of 50% (m/m).

Excipients: calcium hydrophosphate anhydrous, silicon dioxide colloid, Eudragit of RL 30 D (copolymer weed (ethyl acrylate: methyl acrylate: trimetilammonioetilmetakrilata chloride) 1:2:0,2; sorbic acid), Eudragit of RS 30 D (copolymer weed (ethyl acrylate: methyl acrylate: trimetilammonioetilmetakrilata chloride) 1:2:0,1; sorbic acid), triethyl citrate, polysorbate 80, K 25 povidone, кросповидон, magnesium stearate, gipromelloz (5 MPas.с), macrogoal 4000, ferrous oxide red (E172), ferrous oxide yellow (E172), titanium dioxide, talc, saccharin sodium, vanillin, penogasyashchy emulsion.

Description: round biconvex tablets of svetloyokorichnovy color, on a break are visible: a cover of svetloyokorichnevy color and a kernel from brown till svetloyokorichnevy color.

Pharmacological properties:

- reduces permeability of capillaries, renders venotoniziruyushchy, antiedematous, antiinflammatory and angioprotektorny action.

- interferes with activation of the lizosomalny enzymes splitting proteoglycan, raises a tone of a venous wall, eliminates venous stagnation; reduces permeability and fragility of capillaries. Reduces exudation, reduces a liquid exudate in fabric and accelerates a rassasyvaniye of the existing hypostasis.

- slows down processes of an inflammation, improves microcirculation, promotes a reparation of bodies and fabrics.

Indications to use:

The symptomatic treatment of diseases of veins of the lower extremities which is characterized by chronic venous insufficiency with such symptoms as: pains and feeling of weight in legs, night spasms of gastrocnemius muscles, a skin itch and hypostases of legs (including a varicosity).

Route of administration and doses:

Inside, on 1 tablet 2 times a day (in the morning and in the evening): to swallow, without chewing, washing down with a small amount of liquid, before meal.

Duration of use is defined by expressiveness of symptoms of a disease and can be rather long.

Features of use:

Efficiency and safety at children's age was not studied therefore use of drug at children's age is not recommended.

Attention! It is necessary to carry out strictly all additional doctor's instructions as that: bandaging of legs, wearing elastic stockings, cold foot baths. All instructions have to be observed strictly!

At sudden emergence of strongly expressed symptoms (especially on one leg), such, as: severe hypostasis, skin discoloration, feeling of tension, heat, pain, – it is necessary to see a doctor as they can be symptoms of a serious disease – a vein thrombosis of the lower extremities immediately.

Side effects:

Allergic reactions: the feeling of heat, urticaria, skin rash, a skin itch, is rare – an acute anaphylaxis; dyspepsia (including nausea).

If you observe kakiye-Yolibo the undesirable phenomena at administration of drug, report about them, please, to your attending physician.

Interaction with other medicines:

Strengthens effect of indirect anticoagulants.

Contraindications:

Hypersensitivity to any of drug components.

With care: a concomitant use with indirect anticoagulants, age up to 18 years (efficiency and safety is not studied).

Use at pregnancy and in the period of a lactation: use at pregnancy and in the period of a lactation is not recommended, in view of lack of the experimental data on use.

Overdose:

About drug overdose cases it was not reported so far. In case of overdose it is necessary to see behind consultation a doctor who has to make the decision on necessary actions.

Storage conditions:

List B. To store at a temperature from 15 °C to 25 °C, in the place, unavailable to children. Period of validity 3 years. Not to use drug after a period of validity!

Issue conditions:

Without recipe

Packaging:

On 20 tablets in the blister from aluminum foil and PVC in a pack cardboard, or on 25 tablets on 2 or 4 blisters are located together with the application instruction in a pack cardboard.