Kuriozin

General characteristics. Structure:

Active agent: zinc the hyalrunate received on a copy-book: sodium hyalrunate, zinc chloride, – 20,5 mg a water bottle.

Excipients: potassium sorbate, sorbitol, water for injections.

Pharmacological properties:

At interaction of hyaluronic acid with molecules of water there is a dispersive matrix filling missing cellular fabric. It forms the natural supporting framework for the cells participating in a wound repair increases activity of granulocytes and macrophages, strengthens proliferation of fibroblasts and an angiogenesis. In comparison with sodium hyalrunate, hyalrunate of zinc has bacteriostatic action concerning many bacteria.

Pharmacokinetics. At topical administration it is practically not soaked up, in plasma the insignificant amount of drug is defined.

Indications to use:

As a part of complex therapy for topical treatment of badly beginning to live, contaminated wounds, ulcers of a shin, decubituses, fistulas, and also for acceleration of normal healing of wounds.

Route of administration and doses:

Outwardly. To apply solution once a day, on the damaged sites of skin in the maximum dose 1 drop/cm2. After preliminary washing of a surface of a wound or, if necessary, 3% solution of peroxide of hydrogen to apply with normal saline solution several drops of Kuriozin® solution on a gauze napkin in the quantity necessary for uniform moistening of all wound surface in the maximum dose 1 drop/cm2.
To cover a wound with a sterile gauze napkin or the bandage which is not sticking to a wound surface. Solution can be applied 2 times a day on strongly becoming wet wounds. Duration of therapy is individual and depends on a form and disease severity.

Features of use:

Does not cause a photosensitization, does not paint skin and linen.

Side effects:

In an initiation of treatment the feeling of easy burning which gradually disappears is possible.
Very seldom on adjacent sites of skin manifestation of allergic reactions (irritation and contact dermatitis) is possible.

Interaction with other medicines:

There are no data on interaction with other medicines.

Contraindications:

Hypersensitivity to any of drug components, pregnancy, the lactation period.

Overdose:

It is not described.

Storage conditions:

At a temperature from 15 to 30 °C. To store in the places unavailable to children.

Issue conditions:

According to the recipe

Packaging:

Solution for external use of 0,205%. On 10 ml of solution in a white polyethylene bottle with a dropper from colourless polyethylene, and with a white polyethylene cap.
One bottle in a cardboard pack with the enclosed application instruction.