Methionine
Producer: JSC AVVA RUS Russia
Code of automatic telephone exchange: A16AA
Release form: Firm dosage forms. Tablets.
General characteristics. Structure:
Active agent: methionine of 250 mg
Excipients: starch of potato 44 mg, methyl cellulose of 3 mg, stearic acid of 3 mg, wheat flour of 18.556 mg, sucrose of 62.486 mg, magnesium a carbonate of 18.264 mg, talc of 0.496 mg, sunflower oil the refined 0.097 mg, wax of bee 0.097 mg, dye an azoruby of 0.004 mg.
Pharmacological properties:
Irreplaceable amino acid, the donator of mobile metalny groups for synthesis of sincaline, phospholipids, implementation of lipotropic effect. Participates in synthesis of adrenaline, proteins, reactions of transmethylation, deamination, decarboxylation and so forth. Participates in exchange of sulfur-containing amino acids, adrenaline, creatinine, cyanocobalamine, ascorbic and folic acids, hormones, enzymes. Has dezintoksitsiruyushchy effect. Has metabolic, hepatoprotective effect. It is easily soaked up in intestines, with urine it is allocated in a small amount.
Indications to use:
Liver diseases (hepatitises, hepatoses, cirrhoses) proceeding with fatty infiltration of hepatocytes; prevention of toxic damages of a liver arsenic, chloroform, benzene, alcohol; deficit of protein of various origin as a part of a combination therapy.
Route of administration and doses:
Inside the adult on 0.5-1.5 g, children 6 years on 0:25 g – 0.5 g 3-4 times a day in 30-60 min. prior to food are more senior.
Course of treatment of 10-30 days or courses for 10 days with 10-day breaks.
Features of use:
It is necessary to appoint drug in the balanced ratio with other amino acids. Unbalanced use of methionine in high doses can have the damaging effect on cells of a liver and other bodies. Drug does not influence ability to driving and occupations potentially dangerous types of activity requiring special attention and speed of mental and motor reactions.
Side effects:
Allergic reactions, nausea, vomiting are possible (owing to an unpleasant smell and taste).
Interaction with other medicines:
It is not described.
Contraindications:
Viral hepatitis, heavy liver failure, hepatic encephalopathy, hypersensitivity to drug components. Drug is contraindicated to children up to 6 years.
With care. The renal failure (danger of increase of a hyperazotemia) is not recommended reception of Methionine at a viral hepatitis.
Use at renal failures
It is contraindicated at a viral hepatitis, a heavy liver failure, hepatic encephalopathy.
Use for children
Drug is contraindicated to children up to 6 years.
Overdose:
Symptoms: lowering of arterial pressure, tachycardia, disorientation.
Symptomatic treatment.
Storage conditions:
To store drug in the dry, protected from light place at a temperature not above 25 °C. To store in the place, unavailable to children.
Issue conditions:
Without recipe
Packaging:
Tablets, покр. film cover, 250 mg: 10, 20 or 50 pieces.