Arbivir-Zdorovye, капс. on 100 mg No. 10

General characteristics. Structure:

Active ingredient: 1 capsule contains 1-metil-2-(фенилтио) marked) - 3-karbetoksi-4-(dimethylamine) marked) - monohydrate hydrochloride 5-hydroxy-6-bromindol in terms of anhydrous substance of 100 mg; excipients: potato starch, povidone, cellulose microcrystallic, calcium stearate, silicon dioxide colloid anhydrous, gelatin, yellow decline of FCF (Е 110), titanium dioxide (Е 171), понсо 4R (Е 124).

Pharmacological properties:

Antiviral means with immunomodulatory action which specifically suppresses influenza viruses And yes In, the heavy acute respiratory syndrome (HARS). Prevents contact and penetration of viruses into cells, suppressing merge of a lipidic cover to membranes of cells. Has interferonindutsiruyushchy effect, stimulates humoral and cellular reactions of immunity, phagocytal function of macrophages, increases resistance of an organism to viral infections. Reduces the frequency of development of the complications connected with a viral infection.
The therapeutic effectiveness at viral infections is shown in decrease in the general intoxication and cellular displays of a disease, disease duration is reduced. Medicine belongs to low-toxic drugs (LD50> of 4 g/kg), has no negative impact on a human body at use in the recommended doses.
Drug is quickly soaked up in a digestive tract. The maximum concentration is reached in 1,2 h after reception in a dose of 50 mg, in 1,5 h – after reception in a dose of 100 mg. The elimination half-life makes 17 - 21 h. About 40% of drug are removed in not changed view with excrements (38,9%) and with urine (0,12%). Within the first days 90% of the entered dose are removed.

Indications to use:

Prevention and treatment of flu A and B, acute respiratory viral infections, including complicated. As a part of complex therapy of chronic bronchitis, pneumonia and a recurrent herpes infection.
As a part of complex therapy of acute intestinal infections of a mouth of a virus etiology at children 6 years are more senior.

Route of administration and doses:

Apply to children 6 years and the adult are more senior. Accept inside in 30 minutes prior to meal. The single dose makes: children aged from 6 up to 12 years – 100 mg, children aged from 12 years and adult – 200 mg (2 capsules on 100 mg).
For nonspecific prevention:
at direct contact with patients with flu and other SARS:
- children aged from 6 up to 12 years – 100 mg,
- children aged from 12 years and adult – 200 mg of 1 times a day within 10 - 14 days;
in the period of a flu epidemic and other SARS, for the prevention (prevention) of complications of chronic bronchitis, a recurrence of a herpes infection:
- children aged from 6 up to 12 years – 100 mg, children aged from 12 years and adult – 200 mg 2 times a week within 3 weeks.
For treatment
Flu, other SARS without complications:
- children aged from 6 up to 12 years – 100 mg, children aged from 12 years and adult – 200 mg 4 times a day (each 6 hours) within 5 days;
flu, other SARS with complications (bronchitis, pneumonia and others):
- children aged from 6 up to 12 years – 100 mg, children aged from 12 years and adult – 200 mg 4 times a day (each 6 hours) within 5 days, then accept a single dose within 4 weeks once a week.
In complex treatment of chronic bronchitis, a herpes infection:
- children aged from 6 up to 12 years – 100 mg, children aged from 12 years and adult – 200 mg 4 times a day (each 6 hours) within 5 - 7 days, then accept a single dose 2 times a week within 4 weeks.
Complex therapy of acute intestinal infections of a rotavirusny etiology at children aged from 6 years:
- children aged from 6 up to 12 years – 100 mg, children aged from 12 years and adult – 200 mg 4 times a day (each 6 hours) within 5 days.

Features of use:

Use during pregnancy or feeding by a breast.
Data are absent.

Ability to influence speed of response at control of motor transport or work with other mechanisms.
Does not influence.

Children.
Drug is used to children 6 years are more senior.

Side effects:

Allergic reactions are possible.

Interaction with other medicines:

At interaction of drug with other medicines of negative effects it was revealed not.

Contraindications:

Hypersensitivity to drug. Children's age up to 6 years.

Overdose:

It is noted.

Storage conditions:

Not to apply after the termination of the period of validity specified on packaging.

To store in original packaging at a temperature not above 25 °C.
To store in the place, unavailable to children.

Period of validity - 2 years.

 

Issue conditions:

Without recipe

Packaging:

Capsules on 100 mg No. 10 in the blister in a box.