Intolerance of fructose
Contents:
Description:
Hereditary intolerance of fructose - a hereditary disease at which the organism cannot use food fructose as enzyme of a fosfofruktaldolaz is not produced. As a result in an organism fruktozo-1-phosphate - a fructose exchange product collects, blocking formation of a glycogen and its transformation to the glucose necessary for providing expenses of energy.
Fructose is a carbohydrate which contains in berries, fruit and vegetables. In intestines these products are split on various nutrients. Fructose gets to blood, and with it and to a liver. In a liver under the influence of enzymes, it is split in a glycogen. The glycogen is a form of sugar in which it remains in an organism. In a liver it is synthesized in glucose which is one of the main sources of energy in an organism. The glycogen is a peculiar depot of energy in muscles and a liver which can be used instantly: comes to a brain and blood.
Isomeric forms of D-fructose
Fructose metabolism
Reasons of intolerance of fructose:
The child will inherit from parents defect of a gene which is responsible for production of enzyme which controls work of enzymes of a fruktozofosfataldolaza and fruktozodifosfataza. These enzymes are responsible for digestion of fructose and its splitting on glucose. The probability to inherit defect of a gene from the parent who is his carrier makes 25%. Liver cells completely lose ability to produce this enzyme, so, and to turn fructose into a glycogen. Accumulation of fructose in blood and a liver leads to disbolism when in an organism processes of a zhiroobrazovaniye amplify.
Symptoms of intolerance of fructose:
The use even of a small amount of fructose or sucrose (usual sugar) which in an organism turns into fructose, causes decrease in content of sugar in blood (hypoglycemia). A state is followed by sweating, an involuntary shiver of muscles (tremor), a disorientation, nausea, vomiting, an abdominal pain and sometimes spasms and a coma.
If the patient continues to use the products containing fructose injury of kidneys and a liver and decrease in intellectual functions can develop.
Treatment of intolerance of fructose:
Treatment of intolerance of fructose consists in an exception of a diet of the child of products which contain fructose: fruit, vegetables, berries, juice, sweet porridges. In the acute period of a disease limit the use of fats and proteinaceous food. Appoint vitamin C.
Prevention:
Prevention of intolerance of fructose consists in early detection of genetic predisposition. Newborns are transferred to mixes on the basis of lactose, limit the use of fruit and juice.
