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Таблетки АпонилAponil – the medicine from the NPVS group having febrifugal, analgeziruyushchy and antiinflammatory effect.

Form of release and structure

Drug is produced in tablets a dosage of 100 mg. The main active ingredient – Nimesulide.

Indications to use

  • Pain syndrome of various etiology (tooth, head, postoperative, posttraumatic pain, альгодисменорея);
  • Fever;
  • Inflammatory diseases of a musculoskeletal system (miositis, arthritis, osteoarthritis, bursitis, tendovaginitis).


  • Ulcer and erosive damages of a GIT in the period of an aggravation;
  • Aspirinovy asthma;
  • Gastrointestinal bleeding;
  • Heavy disturbances of functions of a liver and kidneys;
  • Pregnancy in the III trimester;
  • Lactation period;
  • The age is younger than 12 years;
  • Hypersensitivity to medicine components.

Route of administration and dosage

Aponil accept 2 times a day after food, washing down with water.

For adults the dose of drug makes from 50 to 200 mg at one time, on average – 100 mg.

For children of 12 years drug is appointed at the rate of 1,5 mg/kg of body weight, but by no more than 100 mg.

The most admissible daily dose of medicine makes 400 mg for the adult and 5 mg/kg of body weight for the child.

Side effects

  • From bodies of the alimentary system: pains in a stomach, ulcers on a mucous membrane of a GIT, nausea and vomiting, heartburn, diarrhea;
  • From a nervous system: drowsiness, headache, dizziness;
  • From urinary tract: seldom – hypostases, a delay in a liquid organism, blood in urine, an oliguria (reduction of amount of urine);
  • From the hemopoietic system: anemia, agranulocytosis, leukopenia, thrombocytopenia;
  • Allergic reactions: urticaria, rash; in rare instances – an acute anaphylaxis.

At exceeding of a dose emergence of nausea and vomiting is possible. At overdose carry out a gastric lavage and reception of adsorbents. In case of need apply infusional therapy, appoint osmotic diuretics, carry out a symptomatic treatment.

Special instructions

Aponil it is necessary to appoint with care with the increased arterial pressure, heart failure and a diabetes mellitus of the second type.

At an abnormal liver function and kidneys, at stomach ulcer and a duodenum, a lupus erythematosus, at co-administration with diuretic drugs and anticoagulants it is necessary to accept drug in low doses.

With care medicine is appointed to elderly people.


Drugs belong to structural analogs of Aponil: Nayz, Nipulid, Auronim, Flolid, Kokstral, Aktasulid, Nimika, Nimesulide, Prolid, Ameolin, Nimiesang.

Conditions and periods of storage

To store at a temperature not above 25 °C.

Period of validity – 3 years.

Whether you know that:

Four segments of dark chocolate contain about two hundred calories. So if you do not want to recover, better not to eat it is more than two segments in days.