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Atenolol blocks nervous impulses that leads to reduction of frequency and force of cordial reductions. Atenolol possesses hypotensive (reduces pressure), anti-anginal (eliminates myocardium ischemia symptoms) and antiarrhytmic (eliminates disturbances of a cordial rhythm) action.
Within the first days after oral administration of Atenolol it is observed reactive increase in the general peripheric resistance of vessels against the background of reduction of cordial emission. Expressiveness of this action within 1-3 days begins to decrease. Hypotensive action of Atenolol is shown in the form of reduction of a minute and stroke output, decrease in systolic (largest) and diastolic (smallest) arterial pressure.
Reviews of Atenolola demonstrate that the hypotensive effect of drug proceeds 24 hours, and in case of regular use by the end of the second week results are stabilized. Anti-anginal action of Atenolol is directed to decrease in need of a myocardium for oxygen due to reduction of number of cordial reductions. Clinical trials and reviews of Atenolola confirm that drug reduces mortality among the patients who had a myocardial infarction due to decrease in frequency of attacks of stenocardia and ventricular arrhythmias.
From digestive tract after oral administration of Atenolol it is soaked up about 50% of a dose of drug. Linkng with blood proteins – 6-16%. The therapeutic effect of Atenolol can be observed in 2-4 hours after use inside, this effect about days lasts. In a liver it is practically not metabolized. Atenolol is brought by kidneys and at a hemodialysis. In breast milk, through placental and hematoencephalic barriers drug gets in insignificant quantity.
Purpose of drug is reasonable at:
According to the instruction, Atenolol can be applied to prevention and treatment of such diseases as:
Positive reviews about Atenolole confirm its efficiency at complex treatment of a hypertrophic subaortic stenosis and a thyrotoxicosis.
Drug should be accepted before food, without chewing and without crushing, washing down with water. In the instruction to Atenolol the following recommendations are specified: an initial dose at stenocardia – 50 mg, the maximum daily dose – 200 mg, a daily maintenance dose – 25 mg once during the day. Fuller and detailed mode of dosing is defined by the attending physician individually for each patient.
In reviews of Atenolola it is seldom mentioned about side effect, however it is necessary to consider that the organism can react to drug use as follows:
Atenolol's use needs to be finished gradually for the prevention of complications as the withdrawal is characteristic of this drug. It is necessary to consider, the therapeutic dose is higher, the side effects are more often and heavier shown. As reviews of Atenolola testify, slight negative reaction of an organism to drug passes through 2-3 weeks of regular use.
In the instruction to Atenolol diseases at which use of this drug is forbidden are specified, belong to them:
Atenolol's appointment is contraindicated to persons with hypersensitivity to drug components,
Under control of the doctor Atenolol's use by pregnant women and the feeding women, persons of children's and advanced age, and also patients with a myasthenia, psoriasis and a depression is carried out.
Atenolol's storage should be carried out in the dark and dry place where air temperature does not exceed 250C.
Drug period of validity – 3 years.
All properties and Atenolol Nikomed's actions are similar to the corresponding characteristics of Atenolol. Drug Atenolol Nikomed is produced in the form of tablets on 50 or 100 mg. The NIKOMED Denmark AnC company is engaged in Atenolol Nikomed's production.
Name of drug
Atenolol of a tablet 50 of Mg of 30 pieces
Atenolol тбл п / about 50 mg No. 30, Nycomed Danmark Asp
Atenolol of a tablet 50 of mg of 30 pieces
Atenolol тбл п / about 100 mg No. 30, Nycomed Danmark Asp
Atenolol Nikomed of a tablet. 100 mg of N30
According to researches, the women drinking several glasses of beer or wine in a week have the increased risk to develop breast cancer.
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