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Tsipramil

The prices in Internet drugstores:

from 873 rub.

International name: to tsitalopra.

Structure

Active ingredient – a tsitaloprama hydrobromide. Ципрамил в таблеткахAs excipients are used: glycerin of 85%, starch corn, sodium of a kroskarmelloz, lactose monohydrate, microcrystallic cellulose, коповидон, magnesium stearate.

Cover: macrogoal 400, gipromelloza5, titanium dioxide (Е 171).

Pharmacological action of Tsipramil

Tsipramil - antidepressant, selective serotonin reuptake inhibitor.

Tsipramil has very slight ability to contact receptors, including muskarinovy, histamine and adrenoceptors.

Tsipramil in very small degree inhibits P450IID6 cytochrome and thanks to it does not interact with the medicines which are metabolized this enzyme. Tsipramil does not make impact on arterial pressure, on the carrying-out system of heart, on hematologic indicators, and also on function of kidneys and a liver. The antidepressive effect of Tsipramil develops approximately in 2-4 weeks of regular reception. Acceptance of drug does not promote increase in body weight.

After internal use of drug bioavailability of a tsitalopram makes about 80%. Level of the maximum concentration in a blood plasma is reached a poproshestviya of 2-4 hours from the moment of administration of drug. Metabolism happens by demethylation, oxidation and deamination. Constant level of concentration in a blood plasma is established in 1-2 weeks of regular therapy. The elimination half-life makes 36 hours. It is removed with urine and a stake.

Indications to Tsipramil's use

It is used for treatment of depressions of various structure and an etiology at adult patients, and also at treatment hung also obsessivno-kompulsivnykhrasstroystvo.

Contraindications

Tsipramil is contraindicated to persons with hypersensitivity to a tsitalopram or any of the used excipients.

It is necessary to avoid Tsipramil's use in combination with monoaminooxidase inhibitors, including within 14 days from the moment of completion of their reception.

According to the instruction Tsipramil therapy for pregnant women and the feeding women is possible only taking into account a soizmereniye of probable advantage for mother with probable harm for the child. Researches about safety of reception of Tsipramil during pregnancy and in the period of a lactation were not conducted.

Tsipramil's dosage and route of administration

Drug is appointed once at any time, regardless of meal.

At treatment of depressions: appoint 20 mg of drug a day. In case of need the dose can be raised to 60 mg/days.

At therapy of panic frustration, within the first week write out 10 mg a day, then the dose raises to 20 mg. If necessary the dose can be raised to 60mg/days.

To patients 65 years the recommended dose are more senior makes 20 mg a day, with possible increase to 40 mg a day. With a liver failure it is recommended to patients to accept drug small doses, the most admissible dose of 30 mg a day. At easy and so-so it are not required for the expressed renal failure dose adjustment.

Side effects of Tsipramil

Side effects of drug have transistor and slight character, can be shown in the first weeks of treatment, in process of improvement of a condition of the patient weaken. At Tsipramil and analogs side effects can be shown in a look: dryness in a mouth, drowsiness, nausea, weaknesses, a diarrhea, the increased sweating, a tremor, sleeplessness, sexual disturbances.Ципрамил в упаковке

On the received comments Tsipramil therapy can become the reason of small decrease in pulse rate. With low heart rate Tsipramil's reception can cause bradycardia in patients.

Extremely seldom when using high doses of drug emergence of convulsive attacks is possible.

The comments received about overdose by Tsipramil show probability of manifestation of the following symptoms:

  • drowsiness;
  • disturbance of an articulation;
  • coma;
  • the increased sweating;
  • sinus tachycardia;
  • nausea and vomiting;
  • hyperventilation;
  • cyanosis.

The specific antidote does not exist, it is recommended to carry out a symptomatic treatment. After peroral administration of drug the gastric lavage is recommended to be done as soon as possible.

Tsipramil's interaction with other drugs

About chemical incompatibility of Tsipramil of responses it was not received. Tsipramil's combination to inhibitors of a monoaminooxidase can become the reason of hypertensive crisis.

It is not established Tsipramil's interactions with alcohol, however alcohol intake during therapy is not recommended. During clinical tests pharmakodinamichesky interaction with kardiotropny drugs was not revealed.

Special instructions

The patients receiving therapy by antidepressants need careful medical observation, especially at the beginning of a course, because of probable clinical deterioration and manifestation of suicide bents.

Use of selective serotonin reuptake inhibitors on the third trimester of pregnancy can exert a negative impact on psychophysical development of the child. At children whose mothers during pregnancy accepted Tsipramil, the following disturbances are registered: a tremor, irritability, a hypertension, tearfulness, the raised muscle tone, a bad dream. The mentioned disturbances can result from a withdrawal. When using analogs of Tsipramil by pregnant women there should not be a sharp cancellation.

The persons performing potentially dangerous work need to show care during treatment by drug.

Drug storage Tsipramil

To store at a temperature up to +30 °C, in places unavailable to children.

Tsipramil period of storage

5 years.

The prices in Internet drugstores:

Name of drug

Price

Drugstore

Tsipramil of a tablet 20 of mg of 14 pieces

873 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC

Tsipramil тбл 20 mg No. 14, Lundbeck H.

1075 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC

Tsipramil of a tablet 20 of mg of 28 pieces

1686 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC

Tsipramil тбл 20 mg No. 28, Lundbeck H.

2018 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC
 
 
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