Fozikard
Application instruction:
Fozikard – means for a lowering of arterial pressure.
Pharmacological action
According to the instruction Fozikard 
treats group of APF inhibitors. Active ingredient is a part of drug – fozinoprit. In an organism it turns into the active metabolite capable to oppress an angiotensin-converting enzyme (APF). As a result in an organism the chain of biochemical reactions is broken: angiotensin-I does not turn into angiotensin-II, to Ina his vasoconstrictive, so and raising pressure, effect is implemented. This medicine does not change blood circulation in kidneys, a brain or muscles.
Eliminating a vasospasm, Fozikard reduces the general peripheric resistance of vessels, so, and arterial pressure. Drug reduces before - and an afterload by a cardiac muscle. As a result of treatment destruction of bradikinin – biologically active agent which expands vessels is slowed down.
After intake Fozikard is well absorbed, meal can slow down absorption speed. The medical effect begins to be shown in 1 hour, it is maximum in 2-6 hours after reception and remains for days. Therefore for achievement of a lowering of arterial pressure Fozikard is enough to accept once a day.
Transformation of drug happens in a digestive tract and a liver, removal from an organism is carried out through kidneys and with bile.
Fozikard's analogs are such drugs on the basis of a fozinopril as Monopril, Fozinotek.
Release form
Fozikard according to the instruction produce 5, 10 or 20 mg in tablets.
Indications to Fozikard's use
Drug is used with the increased arterial pressure, in complex treatment of chronic heart failure.
Contraindications
It is impossible to accept drug at intolerance of its compound components, in case of an idiopathic or hereditary Quincke's disease in the past including if it arose in response to reception of other analogs of Fozikard from group of APF inhibitors.
With care it is possible to use medicine in case of renal and chronic heart failure of III and IV degrees, at a diabetes mellitus, system diseases of connecting fabric, some heart diseases and kidneys, at elderly people if it is required to keep to a diet with salt restriction.
There are no reviews of Fozikarda from the point of view of its safety at children up to 18 years, and also pregnant women and the nursing women.
Application instruction of Fozikard
Pill is taken inside entirely, irrespective of food, washed down with water. The medical dose and a course of reception are selected in each case individually. Some days before the beginning of a course it is recommended to cancel other anti-hypertensive means. When there is no opportunity to cancel diuretics, Fozikard's dose has to be no more than 10 mg/days.
At arterial hypertension begin to accept Fozikard 10 mg once a day, watching change of pressure. If the desirable level of pressure is not reached, it is gradually possible to increase a dose to 40 mg/days (it is the maximum dose). If monotherapy by drug reduces pressure insufficiently, treatment can be strengthened accession of diuretics.
In schemes 
of the combined treatment of chronic heart failure begin Fozikard's reception with 5-10 mg once a day, if necessary increase a dose gradually. The doctor has to control each increase in a dosage.
At diseases of a liver and kidneys of a dose decline it is not required.
At simultaneous use with antacids Fozikard's absorption decreases, so and his medical action is shown not fully. Therefore between reception of these drugs it is necessary to sustain an interval of 2 hours.
Side effects of Fozikard
According to reviews Fozikard is capable to make sick, disturbances of a chair, an abdominal pain, vomiting, decrease in level of hemoglobin and leukocytes in blood, a headache, emotional lability, sleeplessness, a vision disorder, decrease in formation of urine, allergic reactions.
Name of drug
Price
Drugstore
Fozikard тбл 10 mg No. 28, Zdravloje-Leskovac
294 rub.
Network of the Moscow drugstores of IFC
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