Tablets: round, flat, beige or white color, with slanted edge, on one party – risk and the squeezed-out designation "61C" on both of its sides, on another the logo of firm is engraved (on 10 pieces in blisters, on 2, 5, 10 blisters in a cardboard pack);
Solution for intramuscular and intravenous administration (on 2 ml in ampoules, on 5 ampoules in blister strip packagings, on 1 packaging in a cardboard pack).

Is a part of 1 tablet:

Active agent: a pirenzepina dihydrochloride (in the form of monohydrate) – 25 or 50 mg;
Auxiliary components: lactose, corn starch, colloid silicon dioxide (aerosil 200), magnesium stearate.

Active agent is a part of 1 ampoule (2 ml): a pirenzepina dihydrochloride – 10 mg.

Indications to use

Peptic ulcer of a stomach and duodenum;
Acute stomach ulcer and duodenum.

Contraindications

Paralytic Ilheus;
Hypersensitivity to drug components.

Patients with intolerance of a galactose (deficit of lactase, a galactosemia or disturbance of absorption in glucose galactose intestines) should not apply Gastrotsepin in the form of tablets as most recommended daily dose contains 833,64 mg of lactose.

Patients need to use drug with care with glaucoma, tachycardia and a benign hyperplasia of a prostate.

Route of administration and dosage

Pill needs to be taken before food (approximately for half an hour), washing down them with a small amount of liquid. In cases if there are no other instructions of the doctor, drug is accepted in the daily dose 50-150 mg divided into several receptions. The usual mode of dosing – on 50 mg 2 times a day (in morning and evening).

In certain cases in the first few days therapy there can be a need for reception of an additional dose of Gastrotsepin in the middle of the day. If the patient subjectively feels bystry improvement of a state, it is impossible to reduce the accepted dose or frequency rate of use of drug without approval of the doctor.

The average duration of therapy – 1-1,5 months.

Solution for injections is entered intramusculary or intravenously (slowly within more than 3 minutes or kapelno) for 2-3 days on 10 mg with an interval of 12 hours. For treatment and prevention of a stressful ulcer the recommended dose – 10 mg 3 times a day (each 8 hours). At treatment of a syndrome of Zollingera-Ellison the dose can be increased twice, in hard cases use of 20 mg 3 times a day is possible.

For intravenous injection solution for injections can be mixed with Ringer's solution, isotonic solution of sodium of chloride, 5% solution of glucose or fructose at direct vision (lack of loss of a deposit, opacification or discoloration of solution). The prepared infusion solution needs to be used within 12 hours at its storage at the room temperature.

Side effects

During therapy development of such side effects as is possible: accommodation disturbances, dryness in a mouth, tachycardia, diarrhea, a lock, a headache, an ischuria.

Also there were messages on emergence of an acute anaphylaxis and allergic reactions.

Special instructions

The feeding and pregnant women Gastrotsepin should accept only in cases if the expected advantage of therapy of mother exceeds possible risk for the newborn or a fruit.

Patients with glaucoma are recommended to measure intraocular pressure periodically.

Because of disturbance of accommodation and sight disturbance of ability to manage vehicles and the machine equipment is possible.

Medicinal interaction

Simultaneous use of Gastrotsepin with blockers of H2-histamine of receptors can be followed by more expressed reduction of secretion of hydrochloric acid in a stomach.

At Gastrotsepin's use in combination with antiinflammatory drugs, their effect does not decrease, and also their portability improves.