Nystatin of 500000 PIECES N10x2

General characteristics. Structure:

International and chemical names: Nystatin; 19-mikozaminilnistatinolid;
main physical and chemical properties: tablets, coated color, light yellow with a greenish shade, with a vanillin smell;
structure: 1 tablet contains nystatin 500 000 PIECES;
excipients: lactose monohydrate, starch potato or corn, talc, stearic acid, edible gelatin, gipromeloza, titanium dioxide, vanillin, pyrazolon yellow, KE 10-16 emulsion.

Pharmacological properties:

Pharmacodynamics. Nystatin belongs to antibiotics of half-yen structure and Streptomyces noursei is produced. Nystatin is built in a cellular membrane of mushrooms and breaks its permeability that leads to an exit of the main cellular components and killing.
Nystatin selectively affects a pathogenic drozhzhepodobny fungi of the sort Candida and Aspergillus. Renders fungistatic, and in high doses – fungicidal action. Nystatin resistance develops very slowly.

Pharmacokinetics. At intake nystatin is poorly soaked up, resorptive action is not expressed. The most part of nystatin is allocated with a stake in not changed look.

Indications to use:

Prevention and treatment of candidiases of mucous membranes (oral cavity), skin, digestive organs; prevention of candidiases at long therapy by drugs of group of penicillin and other antibiotics, especially at oral administration of antibiotics of a tetracycline row, levomycetinum, Neomycinum, etc.

Route of administration and doses:

Apply inside. Tablets are swallowed without chewing.
The adult - on 500 000 PIECES (1 tablet), 3-4 times a day; a daily dose – 1,5-3 mln units, in hard cases – 4-6 mln units.
To children 3 years - from 1 000 000 to 1 500 000 PIECES a day, in 2-3 receptions are more senior.
Course of treatment - 10-14 days. If necessary the course is repeated in 2-3 weeks.

Features of use:

Purpose of Nystatin at pregnancy is possible if the estimated advantage for mother exceeds potential risk for a fruit. It is not established whether nystatin with breast milk therefore in need of appointment in the period of a lactation it is necessary to resolve an issue of the breastfeeding termination is emitted.

Side effects:

The dispeptic phenomena (nausea, vomiting, diarrhea, abdominal pains), allergic reactions are seldom possible: skin itch, rashes, fever, fever.

Interaction with other medicines:

At simultaneous use of Nystatin with Clotrimazolum activity of the last decreases.

Contraindications:

Hypersensitivity to nystatin.

Overdose:

Strengthening of side effects of drug. Therapy - symptomatic.

Storage conditions:

To store in dry, protected from light and the place, unavailable to children, at a temperature from 15 °C to 25 °C.

Period of storage – 3 years.

Issue conditions:

According to the recipe

Packaging:

Tablets, coated, on 500 000 PIECES No. 10, No. 10х2 in a blister strip packaging.