Epigen

Epigen of intimas – an antiviral medicine for topical and external use.

Pharmacological action of Epigen

Active component of Epigen has complex effect: antipruritic, antiviral, immunostimulating, antiinflammatory and regenerating.

The mechanism of effect of the active component (the activated glycyrrhizic acid) received from a glycyrrhiza root consists in interruption of replication of viruses at early stages that does not allow them to get into cells.

Release form

Epigen release in the form of light yellow 0,1% of spray for external and topical administration which 1 ml contains 1 mg of active component (the glycyrrhizic acid activated) and excipients: maleic, ascorbic, folic and fumaric acids, propylene glycol, the twin and the water purified.

In plastic cylinders with the sprayer on 60 ml. For intravaginalny use the raspylitelny nozzle is included in the package.

Epigen's analogs

Epigen's analogs on active ingredient are Glitsiram, Glycyrrhizic acid and Epigen лабиаль. These analogs of Epigen have various dosage forms (tablets, granules for solution preparation) and are used as antiviral medicines for oral administration.

Indications to Epigen's use

According to the instruction, Epigen intim is appointed at treatment:

• Human papillomavirus infections, including asymptomatic allocation of a virus of papilloma of the person of high oncogenous risk;
• The infections caused by the Herpes simplex virus (type 1 and 2) and Varicella zoster.

Epigen intim is also appointed for prevention:

• Sharp-pointed condylomas and pathologies of a neck of uterus which cause the Herpes simplex viruses (type 1 and 2), papillomas of the person and a cytomegalovirus;
• Recurrence of infections which causes the viruses Varicella zoster, Herpes simplex (type 1 and 2), papillomas of the person and a cytomegalovirus;
• States which are connected with decrease in local immunity against the background of a candidosis vulvovaginitis, a nonspecific colpitis and a bacterial vaginosis.

Besides, Epigen, according to the instruction, apply as a part of the combined and complex therapy at treatment of a Cytomegaloviral infection, and also at discomfort in the field of generative organs which is followed by burning, an itch and dryness of mucous membranes.

Contraindications

Contraindication to Epigen's use intim is hypersensitivity to the components which are a part of a medicine.

Spray route of administration Epigen

At external use spray Epigen spray from distance 4-5 cm on the struck surface. An optimum therapeutic dose are one-two pressing of the valve of a spray. For intravaginalny use of spray it is necessary to use specially applied nozzle. Men in addition to outside drawing Epigen should inject intim into an outside opening of an urethra.

The scheme of treatment by a medicine depends on a disease.

At treatment of skin infections which are caused by a virus of papilloma of the person spray is applied by 3 times a day before removal of condylomas during the entire period of causal treatment. Against the background of destruction it is necessary to increase the frequency of use to five times a day. Treatment duration – not less than ten days, however therapy can be continued before full healing. To avoid development of a recurrence spray Epigen, according to reviews, effectively to apply three times a day for a month.

The medicine is also applied to prevention of progressing of an infection which is caused by a virus of papilloma of the person. In this case spray Epigen is recommended to apply before sexual intercourse, and also against the background of such provocative factors as:

• Overfatigue;
• Stress;
• Disturbances of microflora;
• Respiratory viral infections;
• Reception of some drugs, namely tsitostatik and antibiotics.

During the entire period of action of provocative factors Epigen intim is applied three times a day (outwardly and intravaginalno).

At treatment of infections which cause the Herpes simplex viruses (type 1 and 2) or Varicella zoster spray Epigen it is necessary to inflict on the center defeats to six times a day for five days. However duration of treatment can be increased at persistent disease before total disappearance of symptoms.

At treatment of genital herpes and Cytomegaloviral infection Epigen, according to the instruction, apply outwardly and intravaginalno up to five times a day for two weeks. After stopping of a recurrence Epigen, according to reviews, effectively to use for 10 days three times a day. Spray is recommended to be applied to prevention of a recurrence of a course of a disease from 20 in the afternoon a menstrual cycle before the termination of periods in the morning and in the evening.

At treatment of a nonspecific vulvovaginitis, a bacterial vaginosis and a candidosis vulvovaginitis Epigen it is necessary to apply 3-4 times a day intravaginalno for 7-10 days. The course of treatment a medicine if necessary can be repeated in ten days. For the period of action of provocative factors spray should be applied outwardly and intravaginalno.

As a preventive antiviral medicine, Epigen is recommended to use before sexual intercourse.

At discomfort in the field of generative organs which is shown as an itch burning and dryness of mucous membranes, spray are appointed for several weeks twice a day. To prevention of emergence of this state Epigen, according to reviews, it is efficient to apply after sexual intercourse.

Symptoms of overdose by Epigen in the instruction are not described.

Medicinal interaction of Epigen

Epigen, according to the instruction, strengthens action of other antiviral medicines (a yodouridin, an acyclovir, interferon).

Intim as a part of a combination therapy of viral diseases with analgetics, nonsteroid antiinflammatory medicines and antibiotics does not lead Epigen's use to significant side effects and change of therapeutic action.

Side effects

Epigen, according to reviews, does not cause the expressed disturbances in work of the main systems of an organism. In rare instances outside spray uses Epigen can cause local allergic reactions, most often in the form of contact dermatitis.

Storage conditions

Epigen treats a number of outside antiviral medicines of non-prescription dispensing (list B). A spray period of validity – 36 months at observance of standard storage conditions and temperature to 30 °C.