Seretid

Seretid – the drug which is applied at diseases of bronchial tubes.

Pharmacological action

Seretid – the combined means as a part of which are a glucocorticosteroid флутиказон and салметерол – the substance expanding bronchial tubes.

Salmeterol oppresses early, late stages of allergic reaction, suppresses a hyperactivity of bronchial tubes.

Flutikazon removes an inflammation at inhalation introduction, promotes reduction of a recurrence of diseases and expressiveness of symptoms. Judging by reviews of Seretida, even at his long use, despite the glucocorticosteroid which is a part, the level of daily development of an adrenal hormone at children and adults remains normal.

Release form

Seretid release in the form of an aerosol and powder for inhalations.

Indications to Seretid's use

Seretid appoint at bronchial asthma the patient with insufficient control of a disease who constantly uses inhalation glucocorticosteroids and sometimes adrenomimetik of short action use drugs; to patients with normal control of a disease who at the same time accept adrenomimetik of long action and inhalation glucocorticosteroids.

Also Seretid patients to whom for control of the course of a disease glucocorticosteroids and who have persistent bronchial asthma – the disease which is followed by daily emergence of symptoms and demanding daily use of drugs for a stop of attacks are appointed can appoint.

There are good reviews of Seretida who is applied as drug to the supporting treatment at the chronic obstructive pulmonary disease (COPD).

Route of administration

Drug Seretid is used only for performing inhalations.

To children after 12 l., the adult recommended such dosages of medicine – 4 inhalations a day at the rate of 50 mkg salmeterola/100 to mkg of a flutikazon – in two steps; 4 doses of Seretid a day at the rate of 50 mkg salmeterola/250 mkg of a flutikazon – in two steps; 4 inhalations a day at the rate of 50 mkg salmeterola/500 mkg of a flutikazon – in two steps.

To children of 4-12 l. such dosages of Seretid – 4 inhalations a day at the rate of 50 mkg salmeterola/100 are recommended to mkg of a flutikazon – in two steps.

In Seretid's instruction it is specified that in the course of treatment the dosage needs to be lowered: if after use of two doses symptoms can be checked, it is desirable to pass to one inhalation a day.

At HOBL the adult appoint no more than 4 inhalations in knocks – 50 mkg salmeterola/500 mkg of a flutikazon. Procedures are carried out by two times a day.

Reviews of Seretida confirm that elderly patients and that in whom deviations in work of kidneys, a liver are found do not need correction of the scheme of treatment.

Side effects of Seretid

Seretid can cause pneumonia in patients who undergo treatment concerning HOBL.

Besides, Seretid can cause an allergy, a headache, disturbances of a cordial rhythm (in the patients predisposed to emergence of this symptom), heartbeat, nausea, irritation of a mucous mouth and throat, an abdominal pain, vomiting, taste disturbance, a hypopotassemia, nervousness, spasms in muscles, a hyperglycemia, an arthralgia, a tremor, candidiasis of a mouth and throat, hoarseness of a voice.

In rare instances there can be an uneasiness, the sleep can be interrupted, appear disorder of behavior, including irritability and a hyperactivity – in most cases similar symptoms are observed at children.

Contraindications

Seretid according to the instruction is contraindicated to children to 4 l., to patients at whom the allergy to medicine was shown.

With care appoint Seretid at infections of a respiratory organs of a fungal, virus or bacterial origin, at diabetes, uncontrollable hypertensia, a thyrotoxicosis, a pulmonary tuberculosis, arrhythmia, a hypoxia, coronary heart disease, a subaortal hypertrophic stenosis, a hypothyroidism, glaucoma, a cataract, during a lactation, pregnancy.