Trimetazidin
Application instruction:
Trimetazidin is the medicine relating to group of the drugs improving metabolism (exchange processes) in fabrics of neurosensory bodies and a myocardium in the conditions of disturbance of blood circulation (ischemia) in them.
Pharmacological action of Trimetazidin
Trimetazidin normalizes process of consumption and formation of energy (power metabolism) of the cells having deficiency of oxygen as a result of blood circulation disturbance. According to Trimetazidin prevents decrease in intracellular concentration of the adenosine triphosphoric acid (ATP) which is the main source of energy necessary for maintenance of normal cell activity. In addition drug promotes normal functioning of ion membrane channels, keeping thereby constancy of internal environment (homeostasis) of cells.
In the instruction to Trimetazidin it is noted that his reception increases resistance to shortage of oxygen of cells of a myocardium, the hearing aid and a retina of an eye.
Trimetazidin's use for patients with stenocardia allows to reduce the frequency of emergence of attacks and (tolerance) to exercise stresses increases stability of a myocardium. Besides, against the background of therapy of this medicine use by patients of nitroglycerine significantly decreases.
According to Trimetazidin improves hearing and reduces, and in some cases and completely eliminates dizziness at Menyer's disease.
At intake Trimetazidin is almost completely and very quickly soaked up through a mucous membrane of digestive tract. Its bioavailability makes 90%. The maximum concentration in blood is observed in two hours after acceptance of an initial dose. Trimetazidin is brought generally by kidneys in not changed look.
Indications
This medicine is applied to prolonged treatment of coronary heart disease, both as a part of a combination therapy, and as monotreatment.
According to the instruction Trimetazidin can be used also for treatment of a hearing disorder, a sonitus, cochleovestibular disturbances caused by ischemic disturbances. Besides, indications to Trimetazidin are vascular chorioretinal disorders.
Trimetazidin's dosage
Drug is accepted inside by two – three times a day on 20,0 mg. Duration of use of Trimetazidin is defined by the attending physician individually for each patient, depending on features of a clinical picture of a disease.
Special instructions
Trimetazidin does not exert impact on performance of the work demanding good psychomotor reaction, in particular on ability of control of vehicles.
Contraindications
According to the instruction Trimetazidin is contraindicated to women during pregnancy and breastfeeding, and also to all persons having hypersensitivity to components of this medicine.
Side effects of Trimetazidin
According to Trimetazidin it is rather well transferred by patients. Very seldom it can lead to development of the allergic reactions which are shown emergence of a skin itch and rash. Extremely seldom against the background of Trimetazidin's use there are nausea, vomiting, pains in the field of an epigastrium. If you suffer from individual intolerance of this drug, then Trimetazidin's analogs are also contraindicated to you.
Trimetazidin's analogs
Analogs of any medicine are called the means having the unlicensed international name, identical with it. According to it Trimetazidin's analogs are: Adeksor, Kardazin, Kardimaks, Kardital, Trikard, Energoton, etc.
Storage conditions of Trimetazidin
According to the instruction Trimetazidin it is necessary to store in the dark and dry place at the room temperature. The term of its validity makes two years.
Name of drug
Price
Drugstore
Trimetazidin of MV Tev пролонг.п / about TB of 35 mg No. 60, Merckle
413 rub.
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