Valoserdin

Valoserdin – the combined drug with spasmolytic and sedative action.

Form of release and structure

Valoserdin release in the form of drops for intake – colourless transparent liquid with an aromatic specific smell. On 15 ml, 25 ml and 50 ml in bottles droppers from orange glass or in the brown glass bottles with a screw mouth corked by polymeric traffic jams droppers and the screwed polymeric covers or covers with a dropper on 1 bottle in a cardboard pack.

Active agents are a part of 100 g of drops:

• Phenobarbital – 2 g;
• Etilbromizovalerianat (ethyl ether of α-bromizovalerianovy acid) – 2 g.

Auxiliary components: peppermint oil – 0,14 g; the Spanish hop oil (marjoram oil) – 0,02 g; 95% ethanol (alcohol) – 52,8 g; the purified water – 43,04 g.

Indications to use

Valoserdin appoint as calming and a vasodilator at the following states and diseases:

• Disturbances of work of cardiovascular system;
• Backfilling disturbances;
• Neurosis-like states with an acrimony;
• Condition of excitement with the expressed vegetative manifestations;
• Tachycardia;
• Enterospasms (as an antispasmodic).

Contraindications

Contraindications to Valoserdin's use are:

• The expressed abnormal liver functions and/or kidneys;
• Porphyria;
• Hypersensitivity to drug components.

Drug is not appointed to the feeding and pregnant women, and also children up to 18 years.

Because of Valoserdin who is a part of absolute ethyl alcohol (it is more than 3 g in a daily dose), it is contraindicated to patient to accept drug with craniocereberal injuries, alcoholism, diseases of a liver and brain.

Route of administration and dosage

Valoserdin accept inside, to food.

One-time dosage – 15-20 drops, it is necessary to dissolve previously in a small amount of water (30-50 ml). Frequency rate of administration of drug – 3 times a day. At tachycardia the single dose can be increased till 40-50 drops.

Duration of therapy is established by individually attending physician.

Side effects

As a rule, Valoserdin is well had even at long use. In rare instances in the afternoon development of drowsiness and slight dizziness is possible.

Long reception of high doses can cause chronic poisoning with bromine. It is shown as:

• Apathy;
• Hemorrhagic diathesis;
• Depressive mood;
• Rhinitis;
• Lack of coordination of movements;
• Conjunctivitis.

At development of any atypical side effects which are not specified in the instruction to drug it is necessary to see a doctor.

Symptoms of overdose of Valoserdin are:

• Slight and medium-weight intoxication – dizziness, drowsiness, psychomotor disturbances;
• Heavy intoxication – a vascular collapse, a coma, breath disturbances, a lowering of arterial pressure, tachycardia, decrease in peripheral reflexes.

After a gastric lavage and reception of absorbent carbon it is recommended to see a doctor.

Special instructions

Before Valoserdin's reception it is necessary to consult with the doctor.

Women during breastfeeding for the period of treatment need to interrupt it.

Long therapy can lead to formation of medicinal dependence, and also to accumulation in a bromine organism with the subsequent poisoning with it.

Valoserdin contains not less than 52% about. ethanol (in the maximum daily dose – 3,09 g of absolute ethyl alcohol).

During treatment performance of potentially dangerous types of activity demanding from patients of the increased concentration of attention and speed of psychomotor reactions is not recommended.

Medicinal interaction

At simultaneous use of Valoserdin to sedative medicines there is strengthening of effect, and alcohol in addition to strengthening of effects of drug can also increase its toxicity.

The phenobarbital which is Valoserdin's part can induce liver enzymes. In this regard it is undesirable to accept it along with medicines which are metabolized in a liver – indirect anticoagulants, antibiotics, streptocides. Also phenobarbital can weaken action of derivatives of coumarin, griseofulvin, glucocorticosteroids, contraceptive means for intake.

The concomitant use of Valoserdin with tranquilizers and neuroleptics can strengthen, and with stimulators of the central nervous system – to weaken action of each of drug components.

Terms and storage conditions

To store in protected from light, the place, dry, unavailable to children, at a temperature up to 25 °C.

Drug period of validity – 3 years.