Epidemic pemphigus of newborns

Description:

Epidemic pemphigus of newborns - the acute contagious disease which is clinically characterized very bystry obrazovaniyoy pustules and distribution on an integument of newborns.

Symptoms of the Epidemic pemphigus of newborns:

The disease begins in the first days of life novorozhyodenny or 7-10 days later. On invariable or slightly erythematic skin within several hours small bubbles of the size of a pea or cherry, with a thin, intense tire and transparent serous-yellowish contents are formed. Their education is preceded by the child's bespoyokoystvo, fever. Then contents grow turbid, become purulent. Over time bubbles increase, extend on all body, their tire bursts, baring bright red, wet, pruritic erozirovanny surfaces from the epidermis remains on the periphery. The discharge of erosion dries up in serous and purulent crusts. Most often porayozhena of area of a navel, stomach, breast, back, buttocks and extremities. Про­цесс can extend also to mucous membranes of a mouth, a nose, eyes, geyonitaly where bubbles are quickly opened, forming erosive surfaces of a round, oval or polycycling form depending on the sizes and forms of the previous bubbles. At the weakened, premature children the disease quickly extends (owing to pus autoinoculation from the opened bubbles), being followed by concern, a bad dream, temperature poyovysheniye to 38-39 °C, appetite loss, a leukocytosis, eosinophilias in blood and the raised SOE. In these cases razyolichny complications are possible: otitises, pneumonia, phlegmon and even sepsis.

The epidemic pemphigus proceeds flashes, tolchkoobrazny rashes of bubbles. After the termination of rashes through short time there can come the disease recurrence again. Without complications бо­лезнь 3-5 weeks last.

Reasons of the Epidemic pemphigus of newborns:

The activator - golden staphylococcus. However nekotoyory authors consider the activator a special type of staphylococcus and even стреп­тококк or filtered, a virus.

Pathogeny. In development of a disease an essential role is played by the special reactivity of skin of newborns which is shown in emergence puyozyry in response to action of a bacterial factor, prematurity, a birth trauma, pregnancy toxicoses.
The disease is very infectious. The main sources of infection are medical personnel (medical sestyora, nurses) or swear at newborns, ill or had recently a pyoderma, and also other suppurative focuses at children (a napriyomer, an infection from an umbilical cord). In spread of an infection can play a role and a carriage of bacilli. In maternity homes there can be epideyomichesky disease outbreaks owing to transmission of infection from one newborn patient to another through hands of medical personnel or linen. In case of epidemic immediate closing of department of babies, disinfection of the room and linen are required. In isolated cases of a zayobolevaniye of sick children isolate. There are data on what after transfer of bacilli carriers from among service personnel for druyogy work of new cases is not observed, and epidemic is liquidated.

Treatment of the Epidemic pemphigus of newborns:

Isolation of patients, antibioticotherapia: penitsillinazorezistentny penicillin (as toksikoprodutsiruyushchy staphylococcus usually produce a penicillinase and are not sensitive to usual penicillin), Kefzolum, цепорин; streptocides, vitamin C and groups B, injections of blood of mother. Bubbles open and carefully delete the remains of tires, grease erosion with disinfecting ointment. Heat baths with potassium permanganate. General treatment: antibiotics.