Steel's disease
Contents:
Description:
Form of a juvenile pseudorheumatism of which the seronegative chronic polyarthritis in combination with system inflammatory process developing at children aged up to 16 years is characteristic.
There are several various forms of arthritis which strike preferential children; some doctors adhere to the following definition of a disease of Steel: this children's disease which main displays are arthritis (which often affects several joints), the alternating fever and the fast-passing red rash. At heavy disease it can sometimes extend to all body and be complicated by increase in a spleen and lymph nodes, and also an inflammation of a pericardium and an iris of eyes.
For the first time the disease is described by the pathologist George Steel in 1897. Typical symptoms of this disease were observed also at adults; Eric Bayuoters in 1971 presented detailed analysis of these cases.
Symptoms of the Disease of Steel:
Arthritis symptoms at Steel's disease can fade into the background owing to the expressed system displays of a disease. Arthritis can be absent in an initial stage of a disease, or proceed in the form of mono - or an oligoarthritis, or to be stopped quickly.
The same joints are surprised, as at other forms of a pseudorheumatism — knee, radiocarpal, talocrural, proximal interphalanx, elbow, humeral, pyastnofalangovy, metatarsophalangeal, coxofemoral, distal interphalanx and visochnochelyustny. At an artrotsenteza inflammatory changes of synovial fluid II of a class, as a rule, come to light, and on roentgenograms of joints puffiness of soft tissues, an intra joint exudate, occasionally — periartikulyarny osteoporosis usually are found, erosive changes and/or ankiloza of bones of a wrist are in some cases observed.
Damage of eyes at Steel's disease:
iridocyclitis
tape-like degeneration of a cornea
the complicated cataract
Etiologies of Steel:
There are several schools which are engaged in studying of causes of illness. One of concepts is that Steel's disease results from an infection. Other idea is based that Steel's disease is an autoimmune disorder. Actually, the etiology of Steel is not established yet.
Treatment of the Disease of Steel:
Treatment at Steel's disease needs to be carried out in a complex and step by step. During the active period of a disease patients need hospitalization, in inactive - outpatient observation and sanatorium treatment. A considerable part of time patients are treated in out-patient conditions in connection with disease duration. In policlinic children continue to receive the combined therapy including drug treatment, LFK, courses of massage and physical therapy. Only prolonged and continuous treatment under control of the doctor and nurse can give positive effect.
In the period of an aggravation treatment includes NPVS, in hard cases in combination with glucocorticoids and immunodepressants (quinolinic derivatives, Penicillaminum, a methotrexate, cyclosporine), and also with Ig human normal
