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Septic shock


Description:


Septic shock is a difficult pathophysiological process, resulting from action of an extreme factor, connected with break in a blood stream of activators and their toxins that causes the excessive, inadequate tension of nonspecific mechanisms of adaptation along with damage of fabrics and bodies and is followed by a hypoxia, hypoperfusion of fabrics, deep disorders of exchange processes.


Symptoms of Septic shock:


Symptoms of septic shock depend on a stage of shock, the microorganism which caused it and age of the patient.

Initial stage: reduction of a mocheotdeleniye, sudden temperature increase higher than 38,3 °, fever, nausea, vomiting, diarrhea and breakdown.

Late stage: concern, feeling of alarm, irritability, thirst owing to reduction of inflow of blood to brain tissues, a cardiopalmus and hurried breathing. Babies and old people the only signs of shock can have a low blood pressure, misting of consciousness and hurried breathing.

The lowered body temperature and reduction of a mocheotdeleniye are widespread late signs of shock. Complications of septic shock are the disseminated intravascular coagulation, renal and heart failure, a round ulcer and dysfunction of a liver.


Reasons of Septic shock:


Septic shock (infectious and toxic, bakteriotoksichesky or endotoxic) develops only at the generalized infections proceeding with massive bacteremia, intensive disintegration of bacterial cells and release of the endotoxins breaking regulation of volume of a vascular bed. Septic shock can develop not only at bacterial, but also at viral infections, invasions protozoa, fungal sepsis, severe injuries and so on.


Treatment of Septic shock:


First of all it is necessary to stop progressing of shock. Usually appoint intravenously liquids and control pulmonary pressure. Injection of whole blood or plasma can lift pulmonary pressure to satisfactory level. For overcoming a hypoxia artificial ventilation of the lungs can be required. Introduction of a catheter to uric ways allows to estimate precisely amount of the urine separated for an hour.

For fight against an infection antibiotics are immediately appointed (intravenously). Depending on what microorganism is a contagium, carry out complex treatment by antibiotics (usually use aminoglycoside in combination with penicillin). At suspicion of a staphylococcal infection apply cephalosporin. If the infection is caused by asporous anaerobic microorganisms, write out chloromycetin or cleocin. However these drugs can cause unpredictable reactions. All means should be used only according to instructions of the doctor. In the presence of abscesses carry out their excision and drainage to clear a suppurative focus.

If administration of liquids does not remove shock, by means of dopastat increase blood pressure that allows to support perfusion of blood in tissues of a brain, liver, a digestive tract, kidneys and skin. As acidosis medicine use bicarbonate (intravenously). Intravenous injections of corticosteroids can improve perfusion of blood and minute cordial emission.



Drugs, drugs, tablets for treatment of Septic shock:


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