Immunoglobulin of the person anti-Chlamidia

General characteristics. Structure:

Active ingredients - specific antibodies to the Chlamydia trachomatis virus;

the stabilizer - glycine (glycine, the aminoacetic acid).

Main properties: drug is immunological the active protein fraction allocated from the blood plasma of the person cleared and concentrated by a fractionation method alcohol, which passed a stage of a virus inactivation solvent-detergentnym by method. Protein content in 1.0 ml of drug from 0:09 g to 0:11 g. Transparent or with insignificant opalescence, colourless or yellowish liquid. In the course of storage emergence of an insignificant deposit which disappears when stirring is possible. Drug contains antibodies to Chlamydia trachomatis. Drug does not contain preservative and antibiotics, in raw materials there are no antibodies to VICh-1, VICh-2, to a virus of hepatitis C and a surface antigen of a virus of hepatitis In (HBsAg).

Pharmacological properties:

The operating basis of drug are immunoglobulins, in particular the immunoglobulin G specific to Chlamydia trachomatis. Specific activity of drug is caused by virus neutralizing action of antibodies. Immunoglobulin G also causes immunomodulatory effect, influencing different links of immune system of the person, increasing nonspecific resistance of an organism.

Indications to use:

Drug is used for the purpose of treatment of a chlamydial infection, in particular with defeat of urogenital ways, including a salpingitis, salpingo-oophoritis, colpitis, urethritis, prostatitis, cystitis, an uretroprostatit, not incubation of pregnancy, infertility, etc.

Route of administration and doses:

Immunoglobulin is entered intramusculary.

For treatment of an urogenital chlamydial infection of adults, including pregnant women, immunoglobulin is entered  by 5 - 6 times, once in 3 days in a dose of 3 ml (2 doses). Drug can be also used in the form of local instillations in an urethra and a vagina in a dose of 3.0 ml (2 doses).

Features of use:

Administration of drug is intravenously forbidden!

Use during pregnancy and feeding by a breast. Long-term clinical experience of use of immunoglobulin indicates that it is not necessary to expect any harmful effects on mother and a fruit at pregnancy or on the newborn.

Immunoglobulin is emitted with breast milk and therefore can promote transfer of protective antibodys from mother to the child.

Side effects:

Reactions to administration of immunoglobulin, as a rule, are absent. In rare instances local reactions in the form of a hyperemia and temperature increase to ^{37.5 0C} within the first days can develop. At certain people with the changed reactivity allergic reactions of various type, and in exclusively exceptional cases - an acute anaphylaxis can develop. In this regard the persons who received drug have to be under medical observation within 30 minutes.

Interaction with other medicines:

In complex therapy it is combined with other groups of drugs. The therapeutic effectiveness of treatment by immunoglobulin against C. trachomatis as monotherapies, and in a combination with an antibiotic Rovamycinum is proved.

Contraindications:

Administration of immunoglobulin is contraindicated to the persons having heavy allergic reactions to introduction of proteinaceous blood preparations of the person in the anamnesis. Or having a serious allergic illness in the anamnesis, in day of administration of immunoglobulin and in the next 3 days antihistaminic drugs are recommended to the patients having allergic diseases. To the persons suffering from immune general diseases (diseases of blood, connecting fabric, nephrite, etc.), it is necessary to enter immunoglobulin against the background of the corresponding therapy.

Overdose:

It was not studied.

Storage conditions:

In dry, protected from light, the place at a temperature from 2 °C to 8 °C. To store in the place, unavailable to children.

Issue conditions:

According to the recipe

Packaging:

In ampoules on 1.5 ml (1 dose) and 3.0 ml (2 doses) on 5 or 10 ampoules in a box with a corrugated insert or with a polymeric insert from a film polyvinyl chloride for placement and fixing of ampoules.