Neokler

General characteristics. Structure:

Active ingredient: 5 mg of a levotsetirizin of dihydrochloride.

Excipients: cellulose microcrystallic, monohydrate of lactose, magnesium stearate, silicon dioxide colloid anhydrous.

Structure of a cover: gipromelloza, titanium dioxide (Е 171), macrogoal 400.

Pharmacological properties:

Antihistaminic drugs of systemic action, piperazin derivatives.

Indications to use:

Neokler – antiallergic antihistaminic medicine for general usage.
Neokler is shown at treatment of the symptoms connected with allergic states, such as:
- allergic inflammation of a mucous membrane of a nose (sneezing, rhinorrhea, itch); small tortoiseshell, including chronic idiopathic small tortoiseshell; seasonal fever (pollinosis); complex therapy of the dermatitis which is followed by an itch and rashes (atopic dermatitis, eczema, contact dermatitis and others); symptoms of allergic conjunctivitis such as itch, dacryagogue, conjunctiva hyperemia; allergic reactions to stings of insects.

Route of administration and doses:

For adults and for children over 6 years – one tablet a day.
The tablet should be swallowed entirely, washing down with water.
Patients with renal failures For patients with a renal failure the dose decline, depending on severity of a disease of kidneys is obligatory.
Patients with abnormal liver functions At patients with abnormal liver functions usually recommended medicine dose is applied.
Patients with abnormal liver functions and kidneys For patients with an abnormal liver function and kidneys the dose decline, depending on severity of a disease of kidneys is obligatory. To children the dose is established depending on body weight. The dose will be defined by the attending physician.

Course of treatment
Seasonal allergic inflammation of a mucous membrane of a nose it is necessary to treat depending on course of a disease. Treatment can be interrupted at once after disappearance of a clinical picture and to renew in case of its repeated emergence.
Treatment of a chronic small tortoiseshell and chronic allergic inflammation of a mucous membrane of a nose can continue till 1 year.

Features of use:

Pregnancy and period of feeding by a breast
Before use of medicine it is necessary to consult with the doctor or the druggist. If the woman is pregnant or plans pregnancy, nurses, she has to inform on it the doctor.

Influence on ability to driving of motor transport and to control of moving mechanisms
Some patients taking medicine Neokler can feel drowsiness, fatigue and weakness. If the patient plans to drive motor transport, to perform potentially dangerous works or to service moving mechanisms, it has to consider possible reaction to this medicine.

Side effects:

At emergence of the first signs of hypersensitivity reaction it is necessary to interrupt drug intake Neokler and without delay to contact the attending physician. Can be symptoms of hypersensitivity: swelled lips, language, the person and (or) a throat, difficulty at a breath and swallowing together with a small tortoiseshell (Quincke's disease), the sudden pressure drop of blood leading to a collapse or shock which can cause death.

Most often meet: dryness in an oral cavity, a headache, fatigue of drowsiness.
Much more rare: fatigue, abdominal pain.
Very seldom found side effects: heartbeat, spasms, vision disorders, hypostases, an itch, rash, urticaria (swelled, reddening and an itch of skin), an asthma, increase in body weight, muscular pains, an agressive behavior or excitement, hepatitis, an abnormal liver function and nausea.

If any of symptoms of side effect there was any sign of side reaction which is not specified in a leaf insert it is necessary to inform on it the doctor or the druggist.

Interaction with other medicines:

Side reactions of interaction with pseudoephedrine, Cimetidinum, ketokonazoly, erythromycin, azithromycin, glipizidy, and diazepam are not found. Little change of clearance of a tsetirizin (16%) at multiple dose with theophylline was observed (400 mg a day), at the same time did not exert impact on a theophylline pharmacodynamics in an organism.

It is necessary to inform the doctor or the druggist on all medicine taken now and on those which were accepted recently, especially about those which are given without recipe.

Contraindications:

- hypersensitivity to any of drug components; hereditary intolerance of a galactose, deficit of lactase (like Lapp) or a glucose galactose absorption disturbance syndrome; heavy renal failures (a heavy renal failure with clearance of creatinine smaller, than 10 ml/min.); children's age (up to 6 years).

Medicine use Neokler with food and drink.
Pill can be taken during food or irrespective of meal, however medicine can work with delay if to accept it together with food. Respect for care at a concomitant use of medicine is recommended Neokler and alcohol.

Overdose:

In case of overdose it is necessary to see a doctor.
The overdose can cause drowsiness in adults, and children have an excitement and concern, especially motive in the beginning, and then drowsiness

The taken measures at overdose:
- the specific antidote for a levotsetirizin is unknown; - the symptomatic and maintenance therapy is recommended. If from the moment of drug intake there passed a little time, it is necessary to wash out a stomach. Levotsetirizin is not brought by means of a hemodialysis.
In case of the admission of the next reception of medicine Neokler
It is not necessary to accept a double dose for the purpose of completion of passed.
Treatment should be continued, adhering to recommendations of the doctor.

Storage conditions:

It is necessary to store in the place, unavailable to children.
To store in original packaging at a temperature below 25 °C, to store in the place protected from light.

Issue conditions:

According to the recipe

Packaging:

The box containing 28 or 30 tablets, coated in blisters on 7 or 10 tablets.