Венарус®

General characteristics. Structure:

Active ingredients: 0,45 g of diosmin, 0,5 g of hesperidin in 1 tablet.

Excipients (kernel): gelatin, magnesium stearate, microcrystallic cellulose, sodium of starch glikolit sodium, talc.

Excipients (cover): polyethyleneglycol 6000, magnesium stearate, gidroksipropilmetiltsellyuloz, sodium lauryl sulfate, titanium dioxide, ferrous oxide red, ferrous oxide yellow.

Pharmacological properties:

Pharmacodynamics. Has angioprotektorny and venotoniziruyushchy effect. Reduces distensibility of veins, raises their tone and reduces venous stagnation; reduces permeability, fragility of capillaries and increases their resistance; improves microcirculation and a lymph drainage. At systematic use reduces expressiveness of clinical manifestations of chronic venous insufficiency of the lower extremities of the organic and functional nature.

Pharmacokinetics. The main release of drug happens to a stake. With urine about 14% of the accepted amount of drug are on average removed.

The elimination half-life makes 11 hours.

Drug is exposed to active metabolism that is confirmed by presence of phenolic acids at urine.

Indications to use:

Venous insufficiency of the lower extremities of the functional and organic nature (heavy feeling in legs, pain, spasms, trophic disturbances); acute and chronic hemorrhoids.

Route of administration and doses:

Inside. The recommended dose at venous and lymphatic insufficiency – 2 tablets a day: 1 tablet – in the middle of the day and 1 tablet – in the evening, during meal.

The recommended dose at acute hemorrhoids – 6 tablets a day: on 3 tablets in the morning and on 3 tablets in the evening within 4 days, then on 4 tablets a day: on 2 tablets in the morning and on 2 tablets in the evening during the next 3 days.

Features of use:

Pregnancy. Experiments on animals did not reveal teratogenic effects. So far there were no messages on any side effects at drug use by pregnant women.

Breastfeeding period. Due to the lack of data on drug excretion in breast milk, administration of drug is not recommended to the feeding women.

At an exacerbation of hemorrhoids purpose of this drug does not replace specific treatment of other proctal disturbances. Duration of treatment should not exceed the terms specified in the section "Route of Administration and Doses". If symptoms do not disappear after the recommended therapy course, it is necessary to conduct proctologic examination and to reconsider the applied therapy.

In the presence of disturbances of venous blood circulation the maximum effect of treatment is provided with a therapy combination to the healthy (balanced) way of life: it is desirable to avoid long stay in the sun, long stay standing, and also decrease in excess body weight. Foot walks and, in certain cases, wearing special stockings, promotes blood circulation improvement.

Influence on ability to manage vehicles, mechanisms and to be engaged in other types of activity demanding the increased concentration of attention. Does not influence.

Side effects:

Frequency of development of undesirable reactions is presented as follows: very often (≥1/10 cases), it is frequent (≥1/100 and <1/10 cases), infrequently (≥1/1000 and <1/100 cases), is rare (≥1/10000 and <1/1000 cases) and is very rare (<1/10000 cases).

Undesirable reactions which frequency of development it is not possible to estimate according to available data have the designation "frequency is unknown".

From the central nervous system: seldom – dizziness, a headache, a febricula; frequency is unknown – spasms.

From digestive tract: often – diarrhea, dyspepsia, nausea, vomiting; infrequently – colitis; frequency is unknown – abdominal pains.

From respiratory system, bodies of a thorax and a mediastinum: frequency is unknown – irritation in a throat, a stethalgia.

From integuments: seldom – rash, an itch, urticaria; frequency is unknown – dermatitis allergic, a hyperemia, the isolated face edema, lips, a century, in exceptional cases a Quincke's disease.

If any of the undesirable reactions specified in the instruction are aggravated, or you noticed other undesirable reactions which are not specified in the instruction, report about it to the doctor.

Interaction with other medicines:

It was not noted. It is necessary to inform the attending physician on all accepted medicines.

Contraindications:

Hypersensitivity to the active components or excipients which are a part of drug. Administration of drug is not recommended to the feeding women.

Overdose:

Cases of overdose are not described. At drug overdose immediately ask for medical care.

Storage conditions:

Period of validity - 2 years. Not to use after a period of validity. In the dry, protected from light place at a temperature not above 25 °C. To store in the place, unavailable to children!

Issue conditions:

According to the recipe

Packaging:

Tablets, coated 500 mg. On 10 or 15 tablets, coated, in a blister strip packaging. On 2, 3, 4, 6, 7, 8, 9 blister strip packagings together with the application instruction place in a pack from a cardboard.