Ginkofar

General characteristics. Structure:

Akivny substance: 40 mg of dry extract from leaves of a ginkgo bilobed (Ginkgo bilobae fol. extr. sicc) with the number of 24% of ginkgoflavonoglikozid (derivatives to a kempferol, meletin, an izoramnetin) and 6% of terpenic lactones (a ginkgolida of A, B, C, J and билобалид And); it is given amount of extract corresponds contents of 9,6 mg of ginkgoflavonoglikozid in one tablet;

Other components: lactoses monohydrate, polyvinylpirrolidone, polyethyleneglycol, gidroksipropilmetiltsellyuloza, magnesium stearate, titanium dioxide (E171), silicon dioxide colloid, ferrous oxide yellow.

Pharmacological properties:

Pharmacodynamics. The standardized extract of a ginkgo bilobed, the activator of cellular metabolism, promotes resuming of morphological structure and functional activity of cellular membranes. Has anti-hypoxemic effect on fabrics, including on nervous (improves supply of oxygen and glucose to a brain, билобалид And), interferes with edematization of a brain and retina, and also accelerates a resorption of hypostases, slows down an age reduction of cholinergic receptors and adrenergic α2-рецепторов, improves ability to training and storing. Extract leaves of a ginkgo bilobed, by braking of PAF and increase in elasticity of a cellular membrane of erythrocytes, improves rheological properties of blood. Eliminates a spasm of blood vessels and causes their expansion. Manifestation of it is decrease in viscosity of blood and increase in microblood circulation, respectively medicine improves a coronary and brain blood stream. Extract components leaves of a ginkgo bilobed are neutralized by free radicals and do neurotyre-tread action, including at any neyropatiya and stimulate regeneration of axons of motor nerves (билобалид And).

Pharmacokinetics. At the person absorption of ginkgoflavonoglikozid results in a small intestine. Biological availability of terpenoids to the person makes: for a ginkgolid And 93-100%, a ginkgolid In 79-93% and a biolobalid And - more than 70%. After oral administration in a dose of 50 - 300 mg the maximum concentration is reached in 2-3 hours, and the elimination half-life makes 2-4 hour. Elimination duration - the 24th hour.

Indications to use:

Distsirkulyatorny encephalopathy of different genesis (an effect of a stroke, craniocereberal injuries, at advanced age), in the form of disturbances of attention and/or memory, decrease in intellectual properties, feeling of fear, a sleep disorder; disturbance of peripheric circulation and microcirculation, including arteriopatiya of the lower extremities, Reynaud's syndrome; neurosensory disturbances (dizziness, a ring in ears, the gipoakuziya, a degeneration of a macula lutea is connected with aging, a diabetic retinopathy).

Route of administration and doses:

At distsirkulyatorny encephalopathy of different genesis and disturbances of peripheric circulation it is recommended to accept inside on 1 tablet of Ginkofar 3 times a day after food, washing down with a small amount of liquid.

Duration of a course of treatment has to make 8-12 weeks. The first signs improvement come, as a rule, in 4 weeks from an initiation of treatment. After end of a basic course of treatment 2 times a day after food are recommended further uses of medicine on 1 tablet, washing down with a small amount of liquid. Ginkofar is well had by an organism therefore it can be applied for a long time.

Features of use:

Before an initiation of treatment Ginkofar it is necessary to find out, or pathological symptoms which meet is not a consequence of a basic disease for which it is necessary specific treatments.

Pregnancy and period of feeding by a breast
It is unknown about the facts of a negative impact of drugs with a ginkgo bilobed on a germ and the newborn. However, as experience of its use during pregnancy and feeding by a breast is absent, it is necessary to estimate carefully comparisons of advantage and risk at purpose of treatment in specified the period.

Influence on ability to manage vehicles and moving mechanisms which need big attention of concentration.
Ginkofar does not influence ability to manage vehicles and to service difficult mechanisms, but in case of side effects from a nervous system, it is necessary to avoid such activity.

Side effects:

Very seldom there can be easy disturbances from digestive tract. Persons with hypersensitivity can have a headache, dizziness and skin allergic reactions (reddening, hypostasis, an itch).

Interaction with other medicines:

Drug should not be used at the same time at long therapy by acetylsalicylic acid (aspirin), warfarin, and also thiazide diuretics.

Contraindications:

Hypersensitivity to any component of drug.

As there are no sufficient data of the children concerning use of this medicine for treatment, it should not be applied at children age up to 12 years.

Overdose:

At single or reusable to overdose there can be disturbances from digestive tract, disturbance of thinking, and also a headache.

Therapy is symptomatic.

Storage conditions:

To store in unavailable to children, the dry place, at a temperature from 15 to 25 °C.

Issue conditions:

Without recipe

Packaging:

Drug is packed on 10 tablets in the blister, on 2 or 6 blisters in a cardboard box.