Andipal Aveksima

General characteristics. Structure:

Active ingredients: 250 mg of metamizole sodium (analginum), 20 mg of phenobarbital, 20 mg of Bendazolum (Dibazolum), 20 mg of a papaverine of a hydrochloride.

Excipients: potato starch, talc, stearic acid, calcium stearate.

Pharmacological properties:

Pharmacodynamics. The combined drug. The combination of components of drug leads to mutual strengthening of their pharmacological action.

Metamizole sodium - derivative pyrazyl ketone, has analgeziruyushchy and febrifugal effect.

Bendazolum (Dibazolum) - vazodilatiruyushchy means; possesses vasodilating action, stimulates function of a spinal cord. Has direct spasmolytic effect on unstriated muscles of blood vessels and internals. Facilitates synoptic transfer in a spinal cord.

Papaverine a hydrochloride - the antispasmodic, has hypotensive effect, reduces a tone and weakens unstriated muscles of internals and vessels.

Phenobarbital, in small doses renders sedation and strengthens action of other components.

Indications to use:

— a pain syndrome (poorly or moderately expressed) at spasms of smooth muscles of internals: renal colic, bilious colic, intestinal colic; dyskinesia of biliary tract; postcholecystectomy syndrome; spasm of ureters and bladder; альгодисменорея;

— brain vasospasm, migraine;

— as auxiliary medicine: a pain syndrome after surgical intervention and diagnostic procedures.

Route of administration and doses:

Inside, to adults and children 8 years on 1 tablet of 2-3 times/days are more senior. Use duration without consultation of the doctor should not exceed 7 days.

Features of use:

Use at abnormal liver functions. Drug use is forbidden to patients with the expressed liver failure.

Use at renal failures. Drug use is forbidden to patients with the expressed renal failure.

Use for children. Drug use is forbidden to children 8 years are younger. To children 8 years on 1 tablet of 2-3 times/days are more senior

At long (more than 7 days) use control of a picture of peripheral blood and a functional condition of a liver is necessary. In the absence of effect during 3-x days it is necessary to stop administration of drug and to see a doctor.

During treatment it is necessary to refuse occupations potentially dangerous types of activity demanding the increased concentration of attention and speed of psychomotor reactions.

Children and teenagers up to 18 years should use drug only on doctor's orders.

Side effects:

Allergic reactions.

From TsNS: drowsiness, reduction in the rate of psychomotor reactions.

From a GIT: nausea, lock.

From cardiovascular system: arterial hypotension.

At prolonged use: leukopenia, agranulocytosis, abnormal liver function and kidneys.

Interaction with other medicines:

The combination with nitrates (nitroglycerine, Nitrosorbidum, Sustac, etc.), blockers of calcium channels (nifedipine, Corinfarum, etc.), beta adrenoblockers (анаприлин, метопролол, Talinololum, etc.), ganglioblokator (Pentaminum, etc.), diuretics (furosemide, hypothiazid, etc.), myotropic spasmolysants (Dipiridamolum, an Euphyllinum, etc.) strengthens hypotensive effect of the specified drugs.

Simultaneous use with other non-narcotic analgesics can lead to mutual strengthening of toxic effects.

Combined use with the adsorbents knitting and the enveloping means reduces absorption of drug in a GIT.

Contraindications:

— hypersensitivity (including to pyrazyl ketone derivatives);

— oppression of a marrowy hemopoiesis;

— the expressed liver and/or renal failure;

— deficit glyukozo-6-fosfatdegidrogenazy;

— children are younger than 8 years;

— pregnancy;

— lactation period;

— tachyarrhythmias;

— heavy stenocardia;

— collapse;

— dekompensirovanny chronic heart failure;

— closed-angle glaucoma;

— prostate hyperplasia;

— intestinal impassability;

— megacolon.

Storage conditions:

Drug should be stored in dry, protected from light and the place, unavailable to children. A period of validity - 2 years 6 months. Drug cannot be used after expiry date.

Issue conditions:

Without recipe

Packaging:

ON 10 tablets in blister strip packagings, on 1 or 2 strip packagings in a cardboard pack.