Andipal

General characteristics. Structure:

Active ingredients: 0,25 g of analginum (metamizole sodium), 0,02 g of phenobarbital, 0,02 g of Dibazolum (Bendazolum), 0,02 g of a papaverine of a hydrochloride.

Excipients: potato starch, polyvinylpirrolidone low-molecular medical (povidone) M. of m 12600+2700, calcium stearate 1-water, кросповидон (полипласдон), talc.

Pharmacological properties:

Pharmacodynamics. The combined drug. The combination of components of drug leads to mutual strengthening of their pharmacological action.

Metamizole sodium - derivative pyrazyl ketone, has analgeziruyushchy and febrifugal effect.

Dibazolum (Bendazolum) - vazodilatiruyushchy means; possesses vasodilating action, stimulates function of a spinal cord. Has direct spasmolytic effect on unstriated muscles of blood vessels and internals. Facilitates synoptic transfer in a spinal cord.

Papaverine a hydrochloride - the antispasmodic, has hypotensive effect, reduces a tone and weakens unstriated muscles of internals and vessels. Phenobarbital, in small doses renders sedation and strengthens action of other components.

Indications to use:

Pain syndrome (poorly or moderately expressed) at spasms of smooth muscles of internals: renal colic, bilious colic, intestinal colic; dyskinesia of biliary tract, postcholecystectomy syndrome; spasm of ureters and bladder; альгодисменорея.

Brain vasospasm, migraine.

As auxiliary medicine: a pain syndrome after surgical interventions and diagnostic procedures.

Route of administration and doses:

Inside, on 1 tablet 2-3 times a day. Use duration without consultation of the doctor should not exceed 7 days.

Features of use:

At long (more than 7 days) use control of a picture of peripheral blood and a functional condition of a liver is necessary.

In the absence of effect within 3 days it is necessary to stop administration of drug and to see a doctor.

Influence on ability to manage vehicles and mechanisms. During treatment it is necessary to refuse occupations potentially dangerous types of activity demanding the increased concentration of attention and speed of psychomotor reactions.

Side effects:

Allergic reactions.

From the central nervous system: drowsiness, reduction in the rate of psychomotor reactions.

From digestive tract: nausea, lock.

From cardiovascular system: arterial hypotension.

At prolonged use: leukopenia, agranulocytosis, abnormal liver function and kidneys.

Interaction with other medicines:

The combination with nitrates (nitroglycerine, Nitrosorbidum, Sustac, etc.), blockers of calcium channels (nifedipine, Corinfarum, etc.), beta adrenoblockers (анаприлин, метопролол, Talinololum, etc.), ganglioblokator (Pentaminum, etc.), diuretics (furosemide, hypothiazid, etc.), myotropic spasmolysants (Dipiridamolum, an Euphyllinum, etc.) strengthens hypotensive effect of the specified drugs.

Simultaneous use with other non-narcotic analgesics can lead to mutual strengthening of toxic effects.

Combined use with the adsorbents knitting and the enveloping means reduces absorption of drug in digestive tract.

Contraindications:

Hypersensitivity (including to pyrazyl ketone derivatives); oppression of a marrowy hemopoiesis; the expressed liver and/or renal failure; deficit glyukozo-6-fosfatdegidrogenazy; tachyarrhythmias, heavy stenocardia, collapse, dekompensirovanny chronic heart failure; closed-angle glaucoma; prostate hyperplasia; intestinal impassability, megacolon; pregnancy, lactation period.

Storage conditions:

In dry, protected from light and the place, unavailable to children, at a temperature not above 25 °C. A period of validity - 2 years 6 months. Drug cannot be used after expiry date.

Issue conditions:

Without recipe

Packaging:

Tablets. On 10 tablets in planimetric bezjyacheykovy packaging. 1 or 2 planimetric bezjyacheykovy packagings together with application instructions in a pack from a cardboard.