Ringer

General characteristics. Structure:

In 1 l of solution contains in quality of active agent: sodium of chloride of 8,60 g, Calcii chloridum of 0,33 g, potassium of chloride of 0,30 g.

Auxiliary substances - natron caustic, Acidum hydrochloricum, water for injections; what corresponds: sodium (Na+) - 147,00 mmol, potassium (K+) - 4,00 mmol, calcium (Ca2+) - 2,25 mmol, chloride (Cl-of)-155,60 mmol. Theoretical osmolarity: 309 мосмоль.

Pharmacological properties:

Ringer's solution compensates losses of extracellular liquid and the main electrolytes (sodium, potassium, calcium) and chlorides.

Indications to use:

As plasma substituting means in the absence of need for compensation of erythrocytes, including at shock, a collapse, burns, frostbites, long vomiting, diarrhea. Drug is used at dehydration of various genesis, a hyponatremia, hypovolemic shock (as auxiliary therapy), at a metabolic acidosis with liquid loss.

Route of administration and doses:

Enter in/in kapelno in a dose from 500 to 1000 ml/days, average rate of administering - 3,0 ml/kg of body weight an hour or 70 thaws/min. or 250 ml/hour. The general daily dose makes up to 2-6% of body weight.

Features of use:

At prolonged use control of concentration of electrolytes in plasma and a daily urine is necessary. Because of the high level of ions of chloride prolonged use of drug is not recommended.

Side effects:

At introduction of large volume of solution development of acidosis is possible.

At inadequately high dose disturbance of introduction and electrolytic balance, including a hypovolemia, a hypernatremia, a hyperpotassemia, a hypercalcemia, a hyperchloremia is possible.

Interaction with other medicines:

Increase in a delay of sodium in an organism at a concomitant use of the following medicines is possible: non-steroidal anti-inflammatory drugs, androgens, anabolic hormones, estrogen, corticotropin, mineralokortikoid, vazodilatator or ganglioblokator.

At reception with kaliysberegayushchy diuretics, APF inhibitors and drugs of potassium the risk of development of a hyperpotassemia amplifies.

In a combination with cardiac glycosides the probability of their toxic effects increases.

Contraindications:

Hypersensitivity to drug components, dekompensirovanny heart failure, a fluid lungs, wet brain, an oliguria, an anury, acidosis, a hypervolemia, a hyperchloremia, a hypercalcemia, a hypernatremia, the accompanying therapy of GKS.

With care - heart failure, arterial hypertension, an abnormal liver function or kidneys.

Storage conditions:

List B. To store at a temperature from 15 °C to 25 °C. Period of validity: 3 years. Not to use after the period of validity specified on packaging.

Issue conditions:

According to the recipe

Packaging:

On 500 ml of solution in a plastic bottle. 1 bottle together with the application instruction in a pack of cardboard or 10 bottles together with the application instruction in a box cardboard (packaging for hospitals).