Potassium permanganate

General characteristics. Structure:

Active ingredient: 3 g, 5 g or 15 g of potassium of permanganate.

Pharmacological properties:

Pharmacodynamics. Antiseptic agent. At contact with organic matters emits elemental oxygen. The oxide which is formed at manganese permanganate potassium recovery forms with proteins complex connections – albuminates (at the expense of this potassium permanganate in small concentration renders knitting, and in strong solutions the action – irritating, cauterizing and tanning). Has also deodorizing effect. It is effective at treatment of burns and ulcers. Ability of potassium of permanganate to neutralize some poisons is the cornerstone of use of its solutions for a gastric lavage at poisonings.

At hit it is inside soaked up, having gematotoksichesky effect (leads to development of a methemoglobinemia). Drug belongs to the list No. 4 of the list of the drugs, psychotropic substances and their precursors which are subject to control in the Russian Federation.

Indications to use:

Greasing of ulcer and burn surfaces – contaminated wounds, ulcers and burns of skin.

Rinsing of an oral cavity and stomatopharynx – at infectious and inflammatory diseases of a mucous membrane of a mouth and a stomatopharynx (including quinsies).

For washing and syringings at gynecologic and urological diseases – colpitises and uretrita.

For washings – a stomach at the poisonings caused by intake of alkaloids (morphine, aconitine, nicotine), cyanhydric acid, phosphorus, quinine.

Route of administration and doses:

Outwardly, locally. In the form of aqueous solutions for washing of wounds (0,1-0,5%), for rinsing of a mouth and a throat (0,01-0,1%), for greasing of ulcer and burn surfaces (2-5%), for syringings (0,02-0,1%) in gynecologic and urological practice, and also gastric lavages at poisonings.

For dissolution – several crystals place in a glass with warm water and mix, use solution only freshly cooked.

Side effects:

Allergic reactions, when using strong solutions – burns and irritations.

Interaction with other medicines:

Chemically it is not compatible to some organic matters (coal, sugar, tannin) and easily oxidized substances – there can be an explosion.

Contraindications:

Hypersensitivity.

Overdose:

Symptoms: a sharp stomatalgia, on the gullet course, in a stomach, vomiting, diarrhea; a mucous membrane of an oral cavity and a throat – edematous, dark brown, violet color; throat hypostasis, development of mechanical asphyxia, burn shock, motive excitement, spasms, the phenomena of parkinsonism, hemorrhagic colitis, a nephropathy, hepatopathy is possible. At the lowered acidity of a gastric juice development of a methemoglobinemia with the expressed cyanosis and an otdyshka is possible. A lethal dose for children about Z g, for adult 0,3-0,5 g/kg.

Treatment: methylene blue (50 ml of 1% of solution), ascorbic acid (in/in – 30 ml of 5% of solution), cyanocobalamine – to 1 mg, a pyridoxine (in oil – Z ml of 5% of solution).

Storage conditions:

List IV of precursors of PKKN. In the dry place at a temperature from 15 to 25 °C. To store in the place, unavailable to children. A period of validity - 5 years. Not to use after the date specified on packaging.

Issue conditions:

Without recipe

Packaging:

Powder for preparation of solution for external and topical administration. On 3, 5, 15 g in bottles from a tube glass colourless glass or in bottles glass of brown or colourless glass. On Z g, 5 g, 15 g in glass jars of dark glass. On Z g, 5 g, 15 g in packages from a film polyethylene or in the packages thermowelded from paper packaging with a polyethylene covering.

Each bottle, to bank, the package or 10 packages together with the application instruction place in a pack from a cardboard. Bottles, banks and packages (without packs) with the equal number of application instructions place in group packaging.