Алмагель®А

General characteristics. Structure:

Active agents: oxide of aluminum of 4,00%, oxide of magnesium of 1,38%, benzocaine (anaesthesin) of 2,00%.
Excipients: sorbite, methylparahydroxybenzoate, пропилпарагидроксибензоат, butylparahydroxybenzoate, alcohol (1,8%), saccharin soluble, lemon oil, hydroxyethylcellulose, the purified water.
Description: Алмагель®А represents suspension of white or slightly grayish color with characteristic sweetish taste and a fresh characteristic smell of a lemon. At storage, especially at low temperatures, the layer of transparent liquid is allocated for surfaces. At vigorous agitation of a bottle homogeneity of suspension is recovered. Mixes up with water and alcohol.

Pharmacological properties:

Алмагель®А neutralizes free hydrochloric acid in a stomach that leads to reduction of the digesting activity of a gastric juice. Does not cause secondary hypersecretion of a gastric juice. Renders the action local anesthetizing, adsorbing and enveloping, reduces influence of the damaging factors on a mucous membrane.
The therapeutic effect after administration of drug occurs in 3-5 minutes and proceeds on average 70 minutes.

Indications to use:

Peptic ulcer of a stomach and duodenum in an aggravation phase; acute gastritis, chronic gastritis with the increased and normal secretory function in an aggravation phase; duodenitis, enteritis; hernia of an esophageal opening of a diaphragm, reflux esophagitis; functional disorders of intestines, colitis; discomfort and pains in epigastriums at an error in a diet, after the use of coffee, nicotine, alcohol; preventively at treatment by glucocorticosteroids and non-steroidal anti-inflammatory drugs.
In a complex of medical actions Almagel®A appoint sick diabetes.

Route of administration and doses:

INSIDE! On doctor's orders, on 1 - 3 dosing (tea) spoons, depending on sharpness of a case, 3 - 4 times a day for half an hour to food and in the evening before going to bed.
At children drug is used strictly on doctor's orders: to children up to 10 years appoint 1/3 doses for adults, and to children from 10 to 15 years - on 1/2 doses for adults.
At the disease which is followed by nausea, vomiting and pains, treatment is begun with Almagel®A, and after disappearance of the listed symptoms passed to Almagel reception.
Preventions: the interval between reception of Almagel®A and other medicines has to make 1 - 2 hour; it is not recommended to accept drug in the doses exceeding 16 spoons a day or if apply such dose, duration of a course of treatment has to make no more than 2 weeks; at long administration of drug it is necessary to provide sufficient
receipt with phosphorus food; before reception the bottle should be shaken up!
Pregnancy and lactation: It is not recommended to appoint Almagel®A longer than 3 days at pregnancy. To avoid appointment to nursing mothers.

Features of use:

Use of drug for patients with a heavy usual lock is not recommended; at symptoms of an acute appendicitis; in the presence of a metabolic alkalosis, cirrhosis, heavy heart failure; in the presence of ulcer colitis, a divertuculosis, colostomy or an ileostomy (the increased risk of development of disturbances of water and electrolytic balance); chronic diarrhea; acute hemorrhoids; renal failures (clearance of creatinine <30 ml/min.; danger of development of a gipermagniyemiya and aluminum intoxication).

During treatment by Almagel A it is necessary to avoid alcohol intake and acids (lemon juice, vinegar, etc.), because of a possibility of weakening of the local anesthetizing effect of benzocaine.

At administration of drug there is a numbness and anesthesia of a mucous membrane of an oral cavity and language. This phenomenon passing also does not demand therapeutic measures.

Drug does not contain sugar that allows to accept it sick diabetes.

Drug contains sorbitol which is contraindicated at inborn intolerance of fructose.

Influence on ability of driving and work with mechanisms

Almagel A does not exert impact on ability of control of motor transport and work with mechanisms. At reception in the recommended daily dose the alcohol which is contained in drug does not exert impact on ability of driving and work with mechanisms.

Side effects:

Almagel A can cause a lock which passes after reduction of a dose.

Nausea, vomiting, stomach spasm, change of flavoring feelings, allergic reactions and gipermagniyemiya are in rare instances observed.

At long administration of drug at patients with a renal failure and being on dialysis changes of mood and intellectual activity are possible.

At long reception of high doses of drug along with deficit of phosphorus in food, emergence of osteomalacy is possible.

Interaction with other medicines:

At simultaneous use of Almagel®A can reduce therapeutic effect of antibiotics of a tetracycline row, blockers of histamine H2 receptors, glycosides of a foxglove, salts of iron, ciprofloxacin, fenotiazin, an isoniazid, beta adrenoblockers, indometacin and a ketokonazol. Side effect: In some cases at reception of drug there can be a change of flavoring feelings, nausea, vomiting, a spasm of a stomach, pain in epigastric area and a lock which pass after reduction of a dose. At use of high doses can cause drowsiness. Long treatment using high doses of drug and food poor in phosphorus can lead at predisposed patients to development of deficit of phosphorus in an organism, the raised resorption and excretion of calcium with urine and to emergence of osteomalacy. Therefore at long administration of drug it is necessary to provide sufficient receipt with phosphorus food. At patients with chronic insufficiency of kidneys, except osteomalacy, hypostases of extremities, dementia and a gipermagniyemiya can be observed.

Contraindications:

hypersensitivity to drug components, the expressed renal failure, Alzheimer's disease, early children's age (up to 1 month). Not to appoint along with streptocide ми because of existence in anaesthesin drug!

Overdose:

At single exceeding of a dose other signs of overdose except a lock, a meteorism, feeling of metal taste are not observed.

At long reception of high doses the nephrocalcinosis, emergence of heavy locks, easy drowsiness, a gipermagniyemiya are possible. Also signs of a metabolic alkalosis can be observed: change of mood or intellectual activity, numbness or muscle pain, irritability and bystry fatigue, breath delay, unpleasant flavoring feelings.

It is necessary to take measures for bystry removal of a medicine from an organism by means of a gastric lavage (induction of vomiting, reception of absorbent carbon) at once.

Storage conditions:

In the dry and protected from light place at a temperature not above 25 °C. Not to allow freezing! A period of validity of 5 years from the date of production.

Issue conditions:

Without recipe

Packaging:

Suspension in glass bottles on 170 ml with the dosing spoon; suspension in plastic bottles on 170 ml with the dosing spoon.