Septefril

General characteristics. Structure:

Chemical name: the 1,10-decamethylene-bis (N, N 1-dimetilmetoksikarbonilmetit) ammonium dichloride; main physical and chemical properties: tablets of white color, with a flat surface, risky and a facet; structure: 1 tablet contains decamethoxynum 0,0002 g; excipients: calcium stearate, icing sugar.

Pharmacological properties:

Pharmacodynamics. Decamethoxynum  concerns  to  group  of bischetvertichny  ammonium connections, shows antiseptic action. Because decamethoxynum is
surface-active substance, it changes permeability of a microbic cell, causing its destruction and death what antiseptic action of drug is based on.
Decamethoxynum has a wide range of antimicrobic action (diphtheria korinobakteriya, gnoyetvorny cocci, including staphylococcus, an enterobakteriya, including pseudo-monads,
sporous microorganisms, the elementary, drozhzhepodobny fungi, dermatomitseta; viruses).
At  therapy  by decamethoxynum resistant forms of microorganisms form slowly.
Decamethoxynum increases sensitivity of bacteria to antibiotics, affects microbic cells bakteritsidno, sporotsidno, fungitsidno.
Decamethoxynum    does not oppress a specific and nonspecific  immune responsiveness of a human body.
The maximum action of decamethoxynum comes in 7-10 min. after its reception and continues within an hour.

Indications to use:

Septefril appoint for prevention and treatment of diseases of a throat and an oral cavity (stomatitis, quinsy, tonsillitis, pharyngitis, etc.). Drug is shown for sanitation of carriers of pathogenic staphylococcus and a diphtheritic stick, at candidiasis mucous a mouth and a throat, and also for prevention of infectious complications before operation in an oral cavity and a throat.

Route of administration and doses:

Septefril rassasyvat in an oral cavity, hold in an oral cavity to a full rassasyvaniye.
The adult drug is appointed on 1 tablet, by 4-6 times a day, 3-4 days. Optimum therapeutic concentration in saliva is reached when using 4-6 tablets in days. To children of 5-15 years appoint Septefril on 1 tablet. 3-4 times a day. A pill is taken after food, then for an hour abstain from meal and drink. It is no more than 7 days.

Features of use:

During the periods of pregnancy and a lactation it is necessary to appoint drug with care due to the lack of clinical data on safety of use in this group of patients. At use more than 7 days - disturbances of a microbiocenosis of a throat.

Side effects:

Slight increase of a sialosis which takes place after a tablet rassasyvaniye.

Interaction with other medicines:

Septefril increases sensitivity of bacteria to antibiotics.

Contraindications:

 Septefril's use is contraindicated at   the increased individual sensitivity to drug.
In this dosage form drug is not used for treatment of children up to 5 years.

Overdose:

About drug overdose cases Septefril it was not reported.

Storage conditions:

Store in the unavailable to children, dry, protected from light place at a temperature not above 25 °C.

Validity term - 3 years.

Issue conditions:

Without recipe

Packaging:

On 10 tablets in planimetric strip, bezjyacheykovy packaging.