Tserebrolizat
Producer: Federal state unitary enterprise NPO Mikrogen Russia
Code of automatic telephone exchange: N06BX
Pharm group: Psychoanaleptics
Release form: Liquid dosage forms. Solution for intramuscular introduction.
General characteristics. Structure:
Active ingredient: 1 ml of a hydrolyzate of a brain of cattle in 1 ampoule.
Pharmacological properties:
Pharmacodynamics. Tserebrolizat - drug of brain fabric, contains amino acids and biologically active peptides which get through a blood-brain barrier and directly arrive to nervous cells.
Tserebrolizat improves metabolic processes in brain cells, activates protein synthesis in neurons, increases resistance of tissue of brain to intoxication, a hypoxia, a hypoglycemia; improves a condition of mechanisms of regulation and bioelectric activity of a brain, raises reserve compensatory opportunities of a brain hemodynamics. All this leads to reduction of expressiveness of neurologic deficit.
Indications to use:
— as a part of complex therapy of cerebrovascular insufficiency (distsirkulyatorny encephalopathy;
— ischemic stroke (acute phase and stage of rehabilitation);
— a state after a hemorrhagic stroke;
— traumatic damage of a brain (concussion, a craniocereberal injury, a state after surgical intervention on a brain);
— encephalopathies of various genesis;
— myelipathies;
— neuropathy;
— radiculopathies of various genesis (infectious, toxic, traumatic);
— decrease in concentration of attention at children.
Route of administration and doses:
About 1-5 ml daily or every other day are entered intramusculary. Course of treatment of 20 injections.
After 3-6 monthly breaks treatment tserebrolizaty can be repeated (after consultation with the doctor).
In neuropediatric practice - intramusculary, on 1-2 ml (to 1 ml on 10 kg of body weight) within 10-15 days, with repetition of a course 2-3 times a year.
Features of use:
Use at pregnancy and feeding by a breast. It is contraindicated at pregnancy. With care: drug is appointed in the period of a lactation.
Use at renal failures. It is contraindicated at the expressed renal failures.
Special instructions. With care it is necessary to appoint drug at allergic diathesis, epilepsy.
Side effects:
Drug injections in some cases cause local morbidity, irritation, a hyperemia.
Allergic reactions, increase in the ABP (are possible at the accompanying arterial hypertension).
Interaction with other medicines:
Simultaneous use of a tserebrolizat with antidepressants can cause strengthening of their action.
Contraindications:
— the expressed renal failures;
— pregnancy;
— hypersensitivity.
With care: drug is appointed in the period of a lactation.
Overdose:
Now about cases of overdose of drug it was not reported.
Storage conditions:
List B. To store in protected from light and the place, unavailable to children, at a temperature not above 20 °C. A period of validity - 3 years.
Issue conditions:
According to the recipe
Packaging:
1 ml - ampoules of dark glass (5) - planimetric strip packagings (1) - packs cardboard.
1 ml - ampoules of dark glass (5) - packaging planimetric plastic (2) - packs cardboard.
1 ml - ampoules of dark glass (5) - pallets (2) - packs cardboard.
1 ml - ampoules of dark glass (10) - a pack cardboard.
1 ml - ampoules (10) - packs cardboard.
1 ml - ampoules of dark glass (10) - planimetric strip packagings (1) - packs cardboard.
1 ml - ampoules of dark glass (10) - planimetric strip packagings (2) - packs cardboard.