Viru Mertz

General characteristics. Structure:

Active ingredient: 1 g of a tromantadin of a hydrochloride.

Excipients: lactose, sorbitol of 70% solution, P-Metilgidroksibenzoat, the sorbic acid, hydroxyethylcellulose, water purified.

Antiviral means for topical administration.

Pharmacological properties:

Pharmacodynamics. Has antiviral properties. It is active concerning herpes simplex viruses 1 and 2 types, the surrounding herpes. Inhibits a virus attachment to a surface of a membrane of cells, interferes with penetration of viruses in a cell. Interferes with cell fusion and complicates spread of a virus, changing synthesis of glycoproteins.

Pharmacokinetics. When putting gel absorption the minimum, active agent is not defined on skin in blood and urine.

Indications to use:

The inflammatory diseases of integuments caused by a virus of a herpes simplex, the surrounding herpes.

Route of administration and doses:

Outwardly. Gel is applied on affected areas of skin of 3-5 times a day (if necessary, is more often), slightly rubbing. The course of treatment makes, as a rule, 2-3 days. Treatment by drug needs to be stopped if during use improvement of a state is not observed.

Features of use:

Use during pregnancy and a lactation. Drug is contraindicated at pregnancy and during feeding by a breast due to the lack of clinical data.

Efficiency of treatment by that will be higher, than earlier it is begun (at the first symptoms of an infection within the first 2-3 hours from the beginning of a disease). On a mode of formation of bubbles use of outside antiviral means is not recommended.

Does not prevent transfer of herpes sexually therefore during treatment it is necessary to abstain from sexual contacts, even in the absence of clinical manifestations at the sexual partner. Gel should not be applied in eyes.

Side effects:

Not often (more than 1/1000 and less than 1/100): allergic reactions; very seldom (less than 1/10000): contact dermatitis.

Interaction with other medicines:

 It is not established.

Contraindications:

Hypersensitivity to a tromantadin, methylparahydroxybenzoate, sorbic acid or other components of drug. Drug is contraindicated at children, at pregnancy and during feeding by a breast due to the lack of clinical data.

Storage conditions:

Period of storage - 3 years. After opening a period of storage - 6 months.  Not to use after a period of validity. At a temperature not above 25 °C, in the place, unavailable to children.

Issue conditions:

Without recipe

Packaging:

Gel for external use of 1%, on 5 g in an aluminum tuba with a polyethylene cap. On 1 tuba in a cardboard box with the application instruction.