Артра® Hondroitin

General characteristics. Structure:

Active agent: Chondroitin sodium sulfate *   250 mg 500 mg 750 mg;

* - receiving source: cattle

Excipients: rice flour, silicon dioxide, magnesium stearate. Cover: gelatin, titanium dioxide.

Description: opaque, from white till almost white color, solid gelatin capsules. Existence of a specific smell is allowed. Contents of capsules – powder from white till almost white color.

Pharmacological properties:

Pharmacokinetics. More than 70% of chondroitin of sulfate are soaked up in a digestive tract. Bioavailability of drug makes 13%. At a single dose in a sredneterapevtichesky dose the maximum concentration in plasma is noted in 3-4 hours, in synovial fluid in 4-5 hours. The drug absorbed in a GIT collects in synovial fluid. It is removed by kidneys.

Indications to use:

Osteoarthrosis of peripheral joints, backbone osteochondrosis.

Route of administration and doses:

Inside, washing down with water.
Capsules on 250 mg: inside, the adult on 2 capsules 2 times a day. Capsules on 500 mg: inside, the adult on 1 capsule 2 times a day. Capsules on 750 mg: inside, the adult on 1-2 capsules a day. The recommended duration of an initial course of treatment of 6 months. The period of effect of drug after its cancellation – 3-5 months. Duration of repeated courses of treatment is established by the doctor.

Features of use:

With care patients should appoint with bleedings, and also to patients with tendency to bleedings.

Side effects:

Allergic reactions are in rare instances possible.

Interaction with other medicines:

At simultaneous use of drug with other medicines strengthening of effect of indirect anticoagulants, antiagregant, fibrinolitik is possible. Drug is compatible to non-steroidal anti-inflammatory drugs (NPVP) and glucocorticosteroids.

Contraindications:

Hypersensitivity to drug.
Pregnancy and lactation. It is not recommended to accept during pregnancy and a lactation due to the lack of data.

Overdose:

Cases of overdose are unknown. Treatment: gastric lavage, symptomatic therapy.

Storage conditions:

At a temperature of 10-30 °C, in the dry place. To store in the place, unavailable to children. Period of validity of 5 years. Not to use after a period of validity.

Issue conditions:

Without recipe

Packaging:

60 capsules on 750 mg; 500 mg; 250 mg in a bottle from polyethylene with the screwing-up cover from the same material and the safety valve from a foil and a protective strip from polyethylene. On a bottle paste the label, a bottle cover with polyethylene film and together with the application instruction place in a cardboard pack.
15 capsules in the blister from an aluminum foil / PVC. 4 blisters together with the application instruction place in a cardboard pack.