Бралангин®

General characteristics. Structure:

Active ingredients: 500 mg of metamizole sodium (analginum), 5 mg of a pitofenon of a hydrochloride, 0,1 mg bromide fenpiveriniya.

Excipients: lactose, potato starch, Natrii hydrocarbonas, basin, magnesium stearate, calcium stearate, поливинилпироллидон low-molecular.

Pharmacological properties:

Pharmacodynamics. Bralangin - the combined drug, has anesthetic, febrifugal and spasmolytic effect.

Metamizole sodium is derivative pyrazyl ketone. Possesses soothing, febrifugal and weak antiinflammatory action. Pitofenon, like a papaverine, causes relaxation of smooth muscles of internals due to direct myotropic action. Fenpiveriniya bromide due to holinoblokiruyushchy action makes the additional weakening impact on smooth muscles.

Indications to use:

Pain syndrome at spasms of smooth muscles of internals - renal and bilious gripes, enterospasms, альгодисменорея and other spastic conditions of internals.

Short-term symptomatic treatment at pains after surgical and diagnostic interventions, an arthralgia, neuralgia, an ischialgia, a mialgiya.

Route of administration and doses:

Adults and children are more senior than 15 years I apply! inside (it is better after food) usually on 1-2 tablets 2-3 times a day. The daily dose should not exceed 6 tablets. Duration of reception is no more than 5 days.

Dosage for children of 5-8 years - on 1/2 tablets, 9-12 years - on 3/4 tablets. 13-15 years - on one tablet 2-3 times a day. Reception duration at children no more than 3 days.

Features of use:

Pregnancy and lactation. Use for nursing mothers demands the breastfeeding termination.

During treatment by drug it is impossible to accept alcohol.

In the course of treatment control of maintenance of leukocytes in peripheral blood is necessary. At suspicion on an agranulocytosis or in the presence of thrombocytopenia it is necessary to stop administration of drug.

Influence on ability to manage vehicles and mechanisms. During treatment it is not recommended to drive vehicles and to be engaged in potentially dangerous types of activity demanding speed of physical and mental reaction.

Side effects:

In therapeutic doses drug is usually well transferred. Allergic reactions are possible (skin rash, an itch, a small tortoiseshell, a Quincke's edema; seldom - an acute anaphylaxis; seldom or never - a malignant exudative erythema (Stephens-Johnson's syndrome), a toxic epidermal necrolysis (Lyell's disease).

Seldom (usually at long reception or purpose of high doses) - an agranulocytosis, a leukopenia, thrombocytopenia; renal failure: oliguria. anury, proteinuria, intersticial nephrite; a bronchospasm, decrease in the ABP, a gastralgia, coloring of urine in red color.

Very seldom - anticholinergic effects (dryness in a mouth. decrease sweating, accommodation paresis, tachycardia, ischuria).

It is necessary to report about all side effects to the attending physician.

Interaction with other medicines:

Simultaneous use of Bralangin with other non-narcotic analgesics can lead to mutual strengthening of toxic effects.

Tricyclic antidepressants, contraceptives for intake, Allopyrinolum increase toxicity of drug.

Barbiturates, phenylbutazone weaken effect of metamizole sodium.

Simultaneous use with cyclosporine reduces the level of the last in blood.

Sedatives and tranquilizers strengthen the anesthetizing Bralangin's action.

In need of simultaneous use of the specified and other medicines it is necessary to consult with the doctor.

Contraindications:

Hypersensitivity to drug components, the expressed abnormal liver functions and kidneys.

Genetic absence glyukozo-6-fosfatdegidrogenazy.

Tachyarrhythmia, closed-angle glaucomas, a prostatauxe with a tendency to an ischuria, gastrointestinal impassability and a megaringlet.

Diseases of system of blood (leukopenia, granulocytopenia. the acute "alternating" porphyria).

Heavy arterial hypotension.

Pregnancy (especially the I trimester and the last 6 weeks before childbirth), the lactation period.

Children's age (up to 5 years).

With care and under control of the doctor patients should use drug with the broken function of a liver or kidneys, at tendency to arterial hypotension (systolic pressure is lower than 100 mm hg), to a bronchospasm, and also at the increased individual sensitivity to non-steroidal anti-inflammatory drugs or non-narcotic analgesics.

Children and teenagers up to 18 years should use drug only on doctor's orders.

Overdose:

Symptoms: vomiting, decrease in the ABP, drowsiness, confusion of consciousness, nausea, vomiting, pains in epigastric area, an abnormal liver function and nights, a spasm. The victim should stop administration of drug and to address to the doctor.

Treatment: gastric lavage, absorbent carbon, symptomatic therapy.

Storage conditions:

To store in the dry, protected from light place unavailable to children, at a temperature not above 25 °C. A period of validity - 3 years. Not to use after the term specified on packaging.

Issue conditions:

Without recipe

Packaging:

10, 20 tablets in bank of orange glass or in bank or a bottle from glass melt for medicines; 10, 20 tablets in a plastic container and a plastic bottle. 10 tablets in a blister strip packaging. Each can, container, ringlet, 1; 2 or 10 blister strip packagings in a pack.