Тимоген®

General characteristics. Structure:

Active ingredient: 25 mkg alpha глутамил - tryptophane (Timogen sodium in terms of тимоген).

Excipients: sodium chloride, a benzalkoniya chloride, the water purified.

Pharmacological properties:

Pharmacodynamics. Exerts the regulating impact on reactions of cellular, humoral immunity and nonspecific resistance of an organism. Stimulates processes of regeneration in case of their oppression. Improves the course of processes of cellular metabolism.

Strengthens an expression of differentsirovochny receptors on lymphocytes, normalizes quantity T-helperov, cytotoxic T lymphocytes and their ratio at patients with various immunodeficiency.

Pharmacokinetics. Drug quickly comes to a system blood stream after its intranasal introduction. Alpha глутамил - sodium tryptophane under the influence of peptidases is split on L-glutaminic acid and L-tryptophane which participate in peptide synthesis in an organism.

Indications to use:

- prevention and complex therapy of acute and chronic viral and bacterial diseases of upper respiratory tracts.
- prevention of oppression of immunity, a hemopoiesis, processes of regeneration in the posttraumatic and postoperative periods.
- complex adjuvant therapy for the purpose of correction of secondary immunodeficience at radiation therapy, chemotherapy and an antibioticotherapia.
- complex therapy of the acute and chronic infectious and inflammatory diseases which are followed by decrease in immunity.

In case of need, please, consult with the doctor before administration of drug.

Route of administration and doses:

Locally. To hold a bottle with a thumb for the basis, and a nozzle of the portioning device between average and index fingers. To insert a nozzle of the portioning device into the nasal course in situation vertically up. To press once a nozzle.

The drug is administered intranazalno (in a nose) in doses:

- adult: on 1 dose (one injection) in each nasal course 2 times a day within 10 days with the medical purpose or within 3-5 days with the preventive purpose;

- to children: from 1 year to 6 years 1 dose in one nasal course of 1 times a day, from 7 to 14 years on 1 dose in each nasal course of 1 times a day. Drug is used within 10 days with the medical purpose or within 3-5 days with the preventive purpose. A repeated course of Timogen is conducted not earlier than in 1 month.

Accept drug only according to that route of administration and in those doses which are specified in the instruction. In case of need, please, consult with the doctor before administration of drug.

Precautionary measures at use. It is not required.

Features of use:

Pregnancy and lactation. In connection with insufficient clinical data, administration of drug during pregnancy and during breastfeeding is possible only on doctor's orders if the estimated advantage for mother exceeds potential risk for a fruit or the child. Please, consult with the doctor before administration of drug.

Drug has no features of action at the first reception and at its cancellation. Features of use of medicine by the children and adults having chronic diseases no.

Influence on ability to manage vehicles and mekhaizm. Drug does not exert a negative impact on ability to manage vehicles and to be engaged in other potentially dangerous types of activity demanding the increased concentration of attention and speed of psychomotor reactions.

Side effects:

Allergic rhinitis. Consult with the doctor if you showed the mentioned side effect or other side effects which are not specified in the instruction.

Interaction with other medicines:

Increases efficiency of chemotherapeutic medicines (cytostatic, antibacterial medicines) and radiation therapy.

It is not recommended to use glucocorticosteroid medicines along with high doses.

The immunodepressive effect of high doses of the specified drugs levels an immunopromoting effect alpha глутамил - tryptophane.

Contraindications:

Hypersensitivity to drug components, children's age till 1 year. In case of need, please, consult with the doctor before administration of drug.

Overdose:

At overdose there is a plentiful allocation of a secret of a mucous membrane of a nose stopping after drug withdrawal. Treatment is not required.

At accidental administration of drug inside it is necessary to wash out a stomach water and to see immediately a doctor.

Storage conditions:

To store at a temperature not above 25 °C. To store in the place, unavailable to children. A period of validity - 2 years 6 months. Not to use after the period of validity specified on packaging.

Issue conditions:

Without recipe

Packaging:

Spray nasal dosed 25 mkg / a dose on 10 ml in the bottles of dark glass or polymeric bottles closed by the plastic covers equipped with the pump doser with the plastic case, a nozzle and a protective cap. On one bottle together with the application instruction in a pack from a cardboard. Quantity of doses in a bottle not less than 80.