Тимоген®

General characteristics. Structure:

Active ingredient: 100 mkg alpha глутамил - sodium tryptophane (Timogen® sodium) (in terms of an alpha glutamil - tryptophane) in 1 ml of solution.

Excipients: sodium chloride, water for injections.

Pharmacological properties:

Pharmacodynamics. Exerts the regulating impact on reactions of cellular, humoral immunity and nonspecific resistance of an organism. Stimulates processes of regeneration in case of their oppression. Improves the course of processes of cellular metabolism.

Strengthens an expression of differentsirovochny receptors on lymphocytes, normalizes quantity T-helperov, cytotoxic T lymphocytes and their ratio at patients with various immunodeficiency.

Pharmacokinetics. Drug quickly comes to a system blood stream after its parenteral administration. Alpha глутамил - sodium tryptophane under the influence of peptidases is split on L-glutaminic acid and L-tryptophane which are used by an organism in peptide synthesis.

Indications to use:

In complex therapy of the acute and chronic viral and bacterial diseases which are followed by decrease in immunity:
- viral hepatitis;

- acute and chronic nonspecific diseases of lungs (CNDL): chronic bronchitis, acute and chronic pneumonia;

- diseases of skin and hypodermic cellulose (pyoderma, furunculosis, erysipelatous inflammation);

- in complex therapy of severe diffusion forms of atopic dermatitis;

- in complex therapy of severe mechanical, chemical, radiation and thermal injuries (burn disease);

- complex treatment of a wound and surgical fever, including is purulent - septic complications in the postoperative period;

- during preoperative preparation at planned surgeries for the purpose of prevention of infectious complications and stimulation of processes of regeneration.

- after radiation therapy, chemotherapy, and also long antibacterial therapy in high doses.

Route of administration and doses:

Intramusculary 1 time a day. To adults and children of 14 years on 100 mkg (300-1000 mkg on a course), to children from 6 months to 1 year - 10 mkg, from 1 year to 3 years - 10-20 mkg, from 4 to 6 years - 20-30 mkg, from 7 to 14 years - 50 mkg.

Duration of a course of treatment from 3 to 10 days. Carrying out a repeated course is possible not earlier than in 1 month. Within a year carrying out 4 courses is possible.

Precautionary measures at use: are not required.

The indication of feature of effect of medicine at the first reception or at its cancellation, actions of the doctor and the patient: drug has no features of action at the first reception and at its cancellation.

Features of use:

Pregnancy and lactation. For safety, because of the insufficient number of data, purpose of drug during pregnancy and the period of breastfeeding is possible only if the estimated advantage for mother exceeds potential risk for a fruit or the child.

Drug does not influence ability to manage vehicles and to be engaged in other potentially dangerous types of activity demanding the increased concentration of attention and speed of psychomotor reactions.

Side effects:

Allergic reactions.

Interaction with other medicines:

It is not revealed.

Contraindications:

Hypersensitivity to drug components. Children's age up to 6 months.

With care. There are no features of use of medicine by the children and adults having chronic diseases.

Overdose:

Symptoms of overdose are not described.

Storage conditions:

At a temperature from 0 °C to 10 °C. The instruction on need of storage of medicine for the places unavailable to children: to store in the place, unavailable to children. A period of validity - 3 years. Not to use after the period of validity specified on packaging.

Issue conditions:

According to the recipe

Packaging:

Solution for intramuscular introduction of 100 mkg/ml on 1 ml in ampoules of colourless glass with an overclamping and a ring of a break, or with an overclamping, a notch and a point. On 5 ampoules in a blister strip packaging from a film of polyvinyl chloride and aluminum foil or without foil. 1 or 2 blister strip packagings (with a foil or without foil) together with the application instruction in a pack from a cardboard. On 5 ampoules together with the application instruction in a pack from a cardboard.