Тимоген®

General characteristics. Structure:

Active ingredient: 0,05 g of a timogen of sodium (in terms of тимоген) in 100 g of cream.

Excipients: a liquid paraffin, vaseline, polyoxyethylene sorbitan моно­стеарат (polysorbate 60), glycerin, sorbitan monostearate, stearin alcohol, cetyl alcohol, diethylene glycol monoethyl ether, methylparahydroxybenzoate (нипагин), ksan-tamovy gum, пропилпарагидроксибензоат (нипазол), the water purified.

Pharmacological properties:

Pharmacodynamics. Timogen - the dipeptide exerting impact on reactions of cellular, humoral immunity and nonspecific protection of an organism. Stimuliyoruyet processes of regeneration in case of their oppression, improves the course of processes клеточно­го metabolism.

Timogen increases activity of a 5-ektonukleotidaza and induces Thy-1 eksyopressiya on thymocytes that demonstrates its activating influence on proyotsessa of a differentiation of lymphocytes in a thymus gland. Drug induces an expression diff - rentsirovochny receptors on lymphocytes, normalizes quantity and a ratio of subyopopulyation of lymphocytes at patients with various immunodeficiency.

Normalizes an expression and a ratio about - and antiinflammatory cytokines at various diseases and morbid conditions which are followed by disturbance of an immunoreactivity of an organism.

Indications to use:

As a part of complex therapy:
- atopic dermatitis;

- the atopic dermatitis complicated by a consecutive bacterial infection;

- chronic eczema true and microbic;

- chronic pyoderma, including chronic diffusion streptoderma;

- mechanical, thermal and chemical injuries of integuments.

Route of administration and doses:

Drug is applied with a thin layer on the struck place by 1-2 times a day (in the morning and vecheyory). The recommended daily dose - 2 g of cream (1000 mkg of a timogen). The cream strip from a tuyoba with a diameter of 5 mm with a length of 4 cm has the mass of 1 g.

Course duration - before subsiding of local displays of a disease. The maximum duration of a course - 20 days. After putting cream the struck place does not sleduyot to close a bandage.

Side effects:

Allergic reactions to vspomogayotelny substances are in rare instances possible.

Interaction with other medicines:

It is not observed.

Contraindications:

Hypersensitivity to auxiliary components of drug, the periods of pregnancy and a lactation.

Overdose:

The overdose timogeny is not described. It is experimentally shown that тимоген it is not toxic in the doses exceeding therapeutic in thousands of times.

Storage conditions:

To store at a temperature from 2 °C to 20 °C. To store in the place, unavailable to children. A period of validity - 2 years. Not to apply after the period of validity specified on packaging.

Issue conditions:

Without recipe

Packaging:

Cream for external use of 0,05%. Packaging: on 20 g or 30 g in tubas aluminum or banyoka from glass melt with the tense cover from polyethylene. On one tuba or one bank together with the application instruction in a pack from a cardboard.