Pektolvan of feet

General characteristics. Structure:

Active ingredients: butamirata citrate, гуайфенезин;

1 ml of drug (33 drops) contains a butamirat of citrate in terms of 100% substance - 4 mg, a guayfenezina in terms of 100% substance - 100 mg;

excipients: propylene glycol, polysorbate 80, glycyrrhiza root extract, fragrance food "The Alpine herbs", the water purified ethanol (96%).

Pharmacological properties:

The combined drug having antibechic, mucolytic and expectorant effect. The citrate which is a part of drug of a butamirat belongs to antibechic substances of peripheral action, does not cause dependence, the respiratory center does not oppress.

Antibechic action of a butamirat of citrate is supplemented with expectorant action of a guayfenezin who strengthens secretion of bronchial glands, reduces viscosity of a phlegm and by that improves its otkhozhdeniye.

Butamirata citrate after oral administration is quickly and completely absorbed, for 98% contacts blood plasma proteins. It is metabolized with formation of two metabolites having antibechic effect which more than 90% are removed by kidneys; only a small amount is allocated with excrement. Biological half-life makes about 6 h.

Guayfenezin after oral administration is quickly absorbed from digestive tract. Its insignificant part contacts proteins of a blood plasma. The insignificant quantity – in not changed state is distinguished with urine, mainly in the form of metabolites. Biological half-life makes 1 h.

Indications to use:

The dry, irritating, pristupoobrazny cough of a different origin. Drug can be used for elimination of cough in before - and the postoperative period.

Route of administration and doses:

Apply inside. It is desirable to accept after food. To dissolve the corresponding quantity of drops in 50-100 ml of liquid (water, tea, fruit juice), depending on age. The interval between receptions has to make 4-6 hours.

It is necessary to adhere to dosing depending on the body weight of the patient:

to 7 kg - on 8 drops 3-4 times a day,

7-12 kg - on 9 drops 3-4 times a day,

12-20 kg - on 14 drops 3 times a day,

20-30 kg - on 14 drops 3-4 times a day,

30-40 kg - on 16 drops 3-4 times a day,

40-50 kg - on 25 drops 3 times a day,

50-70 kg – on 30 drops 3 times a day,

70-90 kg - on 40 drops 3 times a day.

Use of bigger amount of liquid increases efficiency of treatment. If Pektolvan Stop appoint to very small children (with body weight less than 7 kg), then the dose can be reduced. Even if the child does not drink all 100 ml of liquid with the medicine dissolved in it, it is impossible to increase quantity of drops of drug (full concentration) in liquid.

Without consultation of the doctor not to use drug longer 7 days.

Features of use:

Use during pregnancy or feeding by a breast.

It is not necessary to use drug in the I trimester of pregnancy.

Use of drug in ІІ, ІІІ trimesters of pregnancy or during feeding by a breast perhaps only if, according to the doctor, the expected therapeutic effect for mother exceeds potential risk for the fruit/child.

It is not known whether citrate or гуайфенезин in breast milk is emitted a butamirat.

Ability to influence speed of response at control of motor transport or work with other mechanisms. During treatment by Pektolvan Stop it is necessary to refrain from potentially dangerous types of activity requiring special attention and speed of motor and mental reactions.

Children. Drug is used to children from 6-month age according to indications (doses and a route of administration are given in the section "Route of Administration and Doses").

Side effects:

If to adhere to the recommended dose, drug is usually well transferred.

Criteria for evaluation of frequency of development of side reaction of medicine: more than 10% - are very frequent, 1-10% - are frequent, 0,1-1% - are rare, 0,01% of-0,1% - isolated cases, less than 0,01% - are extremely rare.

From a nervous system: often – a headache.

Vestibular frustration: often – dizziness.

From a digestive tract: often – nausea, a stomach ache, vomiting, diarrhea, lack of appetite.

From skin and hypodermic cellulose: extremely seldom – a dieback, a small tortoiseshell.

From an urinary system: extremely seldom – an urolithiasis.

Interaction with other medicines:

Guayfenezin strengthens analgetichesky effect of paracetamol and acetylsalicylic acid, effect of alcohol and other substances oppressing the central nervous system.

Muscle relaxants with the central mechanism of action can strengthen undesirable effects of a guayfenezin, especially muscular weakness.

Guayfenezin can cause lozhnopozitivny results of diagnostic tests at which define 5-hydroxyindolacetic acid (a photometric method with use of a nitrosonaftol as reagent) and vanilmindalny acid in urine. It is necessary to stop treatment by drug Pektolvan Stop in 48 hours prior to collecting urine for carrying out this analysis.

Contraindications:

Hypersensitivity to drug components, a myasthenia, І a pregnancy trimester.

Appropriate security measures at use.

Drug use is not recommended more than 7 days. With care it is necessary to apply at asthma, tuberculosis, a pneumoconiosis. Drug is not recommended to be used to patients with the productive cough and/or persistent or chronic cough connected with smoking.

During treatment by Pektolvan Stop the use of alcoholic beverages is not recommended.

Drug contains ethanol.

Overdose:

At overdose signs of toxic action of a guayfenezin – drowsiness, nausea, vomiting, muscular weakness prevail; there is no specific antidote.

Treatment. A gastric lavage, reception of absorbent carbon the general dose to 60 g a day divided into several separate receptions. The symptomatic therapy directed to maintenance of functions of cardiovascular and respiratory systems, functions of an urinary system and electrolytic balance.

Storage conditions:

Period of validity. 2 years. Not to use drug after the termination of the period of validity specified on packaging. To store in the place protected from light at a temperature not above 25 °C. Not to freeze. To store in the place, unavailable to children.

Issue conditions:

Without recipe

Packaging:

On 25 ml in the bottle enclosed in a pack.