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Analginum-quinine

The prices in Internet drugstores:

from 80 rub.

Таблетки, покрытые пленочной оболочкой, Анальгин-хининAnalginum-quinine – the combined analgetic antipyretic.

Form of release and structure

Dosage form – tablets, film coated: round, biconvex, green color (on 10 pieces in the blister, 2 blisters in a pack cardboard).

Active agents as a part of 1 tablet:

  • Metamizole sodium – 200 mg;
  • Quinine a hydrochloride – 50 mg.

Auxiliary components: sodium carboxymethylstarch (примогель), talc, kollidon-25 (povidone), cellulose microcrystallic (Avitsel PH101), magnesium stearate.

Structure of a cover: pigmental green eudragit L 12.5 P (methacrylic acid and methylmethacrylate copolymer), глицерол, titanium dioxide, talc, a macrogoal 400, castor oil, dye (dye blue patent V E131 and quinolinic yellow E104).

Indications to use

  • Pain syndrome of various genesis, including head and postoperative pain, альгодисменорея, miositis, arthralgia, neuralgia, mialgiya;
  • Feverish states at infectious and inflammatory diseases;
  • Bilious and renal gripes (in a combination with spasmolysants).

Contraindications

  • The diseases which are followed by a bronchospasm;
  • Asthma caused by reception of salicylates or other non-steroidal anti-inflammatory drugs (NPVS);
  • Bronchial asthma;
  • Heavy myasthenia;
  • Optic neuritis;
  • Decrease in hearing, disease of a middle and inner ear;
  • Hemopoiesis oppression (neutropenia, agranulocytosis, leukopenia);
  • Heavy dysfunctions of livers/kidneys;
  • The hereditary hemolitic anemia caused by deficit glyukozo-6-fosfatdegidrogenazy;
  • Children's age up to 12 years;
  • Pregnancy and lactation;
  • Hypersensitivity to components of drug or other derivatives of pyrazyl ketone.

With care:

  • Food, medicinal and other forms of an allergy (including a pollinosis);
  • Granulocytopenia;
  • Hypersensitivity to other NPVS.

Route of administration and dosage

Analginum-quinine should be accepted inside, after food: to swallow of tablets entirely and to wash down with enough liquid.

To adults and teenagers 14 years are more senior appoint 1-2 tablets from 1 to 3 times a day.

For children of 12-14 years the recommended dose makes on 1 tablet to 3 times a day.

If the doctor did not appoint other, at a pain syndrome it is possible to accept drug no more than 5 days, at a feverish syndrome – it is no more than 3 days.

Side effects

  • From the central and peripheral nervous system: bystry fatigue, dizziness, sleeplessness, headache, tremor of extremities;
  • From the alimentary system: diarrhea, discomfort and pain in a stomach and epigastric area, nausea, vomiting: seldom – an ulceration of a mucous membrane and bleeding from digestive tract;
  • Allergic reactions: sometimes – urticaria, an itch, an enantema, eczema, a Quincke's disease; seldom – an acute anaphylaxis; in some cases – a bronkhospastichesky syndrome, a toxic epidermal necrolysis, a malignant exudative erythema;
  • From system of a hemopoiesis: agranulocytosis, leukopenia, prothrombinopenia;
  • From cardiovascular system: heart consciousness, stenocardia, faint;
  • From an urinary system: delay of water and electrolytes, renal failure (including anury, oliguria, proteinuria);
  • From sense bodys: vision disorder (reduction of fields of vision, scotoma, diplopia, photophobia, disturbance of color sight, sight opacification), sonitus, hearing easing;
  • Others: fervescence.

Special instructions

At prolonged treatment (more than 7 days) it is necessary to control a pattern of peripheral blood.

It is not necessary to appoint drug along with penicillin, colloid blood substitutes and radiopaque substances.

It is possible to apply along with vitamins, antibiotics and chemotherapeutic means.

In case of development of side effects the patient should stop accept drug and to see a doctor.

Before clarification of the reason it is impossible to apply Analginum-quinine at acute abdominal pains.

At patients with pollinoses and bronchial asthma development of reactions of hypersensitivity is possible.

During treatment it is recommended to refrain from driving of the car and performance of other potentially dangerous types of activity demanding the speed of reactions and special attention.

Medicinal interaction

  • Other analgetics antipyretics: mutual strengthening of toxic effects is noted;
  • Sedatives, tranquilizers: analgeziruyushchy effect of metamizole sodium amplifies;
  • Phenylbutazone, barbiturates: effect of metamizole sodium is weakened;
  • The means blocking neuromuscular transmission: their action is exponentiated;
  • Cimetidinum: the clearance decreases and the quinine elimination half-life increases;
  • Allopyrinolum, tricyclic antidepressants and oral contraceptives: metabolism of metamizole sodium in a liver is broken, its toxicity increases;
  • Cyclosporine: its level in blood decreases;
  • Digoxin: its concentration in a blood plasma increases, action amplifies;
  • Thiamazolum, sarcolysine: the risk of development of a leukopenia increases;
  • Glucocorticosteroids, indirect anticoagulants, peroral hypoglycemic drugs, indometacin: their action amplifies;
  • Inductors of a microsomal oxidation: metabolism accelerates and efficiency Analginum-quinine decreases;
  • Inhibitors of a microsomal oxidation: efficiency of drug and risk of development of its side effects increases;
  • Etanolsoderzhashchy drugs / drinks: their action amplifies;
  • Codeine, propranolol: action Analginum-quinine amplifies.

Terms and storage conditions

To store in dry, protected from light, the place, unavailable to children, at a temperature up to 25 °C.

Period of validity – 5 years.

The prices in Internet drugstores:

Name of drug

Price

Drugstore

Piece tablet 20 analginum-quinine

80 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC

Analginum-quinine тбл п / about No. 20, Pharmachim/Sopharma

97 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC
 
 
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