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Atorvastatin is the hypolipidemic medicine from group of statines intended for decrease in level of cholesterol in blood.
Drug Atorvastatin contains 10 mg of calcic salt and auxiliary components (cellulose, corn starch and talc). Atorvastatin produce 10-80 mg placed in cardboard packaging on 10-30 pieces in the form of tablets.
Atorvastatin is the drug of the directed action reducing the content of cholesterol in blood. The mechanism of action consists in regulation of speed of the GMG transformations in мевалонат.
Patients with the raised cholesterol of hereditary and not hereditary character after the reception given drug can reduce contents lipoprotein density, and also reduce the level of triglycerides.
Atorvastatin received good comments as the medicine reducing synthesis of cholesterol and increasing receptors by surfaces of cells of a liver. After Atorvastatin's course the risk of development of an ischemic disease and myocardial infarction decreases. This drug improves work of cardiovascular system, and also is prophylactic of cardiovascular diseases and a stroke. Atorvastatin's absorption in digestive organs is reached within 2 hours, and bioavailability makes 12-15%. Drug is metabolized in a liver, forms several active metabolites and inactive components. Atorvastatin is brought from an organism within 15-20 hours with urine and a stake.
At patients with disturbances in work of a liver increase in plasma concentration of Atorvastatin can be observed.
Atorvastatin appoint as a part of complex therapy for decrease in level of the general cholesterol in blood, lipoproteins of low density and triglycerides.
Atorvastatin received positive reviews as the drug increasing the maintenance of lipoproteins of high density. Also apply Atorvastatin to improvement of functioning of cardiovascular system and prevention of a hypertension, a diabetes mellitus, a myocardial infarction, coronary heart disease, stenocardia and a stroke.
Atorvastatin has a set of positive reviews as the medicine for children directed for decrease in the general cholesterol and improvement of work of cardiovascular system to the postoperative period.
Atorvastatin's analogs are Atokord, Atomaks, Atoris, Vazator, Lipona, Torvakard and Tulip. These drugs possess similar pharmacological actions and are intended for decrease in level of cholesterol in blood.
Atokord and Torvakard as Atorvastatin's analogs, are effective for treatment of a hypercholesterolemia of hereditary type.
According to the instruction Atorvastatin it is necessary to accept orally 1 time a day, irrespective of meal, but washing down with a large amount of water.
Before purpose of a course of treatment the doctor has to hold the therapeutic events directed to decrease in body weight including the diet and a complex of daily physical exercises is appointed. Atorvastatin it is possible to appoint against the background of observance of an anti-cholesteric diet. Duration of treatment is determined by the attending physician according to diagnostic testimonies of the patient.
According to the instruction Atorvastatin at a lipidemia and a hypercholesterolemia of the mixed type it is necessary to accept 10 mg a day. At a hypercholesterolemia of hereditary type appoint 50-70 mg of drug of 1 times a day.
Children from 12 to 16 years Atorvastatin can accept 10 mg of 1 times a day. If necessary the dosage is raised to 20 mg of 1 times a day. Atorvastatin's instruction orders to adjust surely a dosage to patients at advanced age and with heavy disturbances of functioning of kidneys.
The maximum daily dosage of drug for adult patients should not exceed 80 mg, and for children – 40 mg. Before a course of treatment it is necessary to check functioning of a liver, kidneys and system of digestion.
Atorvastatin is contraindicated at hypersensitivity and existence of allergic reactions to its components, a serious illness of a liver and kidneys, pregnancy and a lactation, at children's age up to 12 years.
It is inadmissible to appoint drug to patients with an individual lactose intolerance and a syndrome of a galactosemia.
With care drug is appointed at alcoholism, a serious illness of the alimentary system, endocrine disturbances, hypotonia, infectious diseases, epilepsy, injuries and after a hemorrhagic stroke.
Atorvastatin can cause a number of side effects. It is possible to carry to them:
Atorvastatin can provoke allergic reactions, including a skin itch, a small tortoiseshell, dermatitis, a bronchospasm, an alopecia. This drug in high dosages strengthens risk of development of fungus diseases, mialgiya, disturbances of memory and increased fatigue.
Name of drug
Atorvastatin of a tablet 10 of mg of 30 pieces
Atorvastatin of a tablet 10 of mg of 30 pieces
Atorvastatin тбл п/пл/о 10 mg No. 30, Vertexum of closed joint stock company
Atorvastatin of a tablet 20 of mg of 30 pieces
Atorvastatin тбл п/пл/о 20 mg No. 30, Vertexum of closed joint stock company
Atorvastatin тбл п/пл/о 10 mg No. 30 *, CJSC Kanonfarm Production
Atorvastatin of a tablet 40 of mg of 30 pieces
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