- Symptoms of System candidiasis
- Reasons of System candidiasis
- Treatment of System candidiasis
Cases of the widespread combined candidiases with damage of internals, with development of barmy sepsis began to register in all countries in connection with broad use of antibiotics for treatment of various diseases.
Symptoms of System candidiasis:
At visceral candidiases mucous membranes of respiratory tracts, digestive tract, urinogenital bodies are most often affected. Barmy defeats of cardiovascular and nervous systems, kidneys, a liver, a spleen, bronchial tubes and lungs (pneumonia), brain tissue, a muscle of heart, blood vessels and other bodies are described. Visceral candidiasis can lead to a septic state which sometimes arises also without the previous damage of internals. These defeats, as a rule, arise at the weakened and exhausted patients suffering from heavy persistent infections or a serious general illness and also at treatment of such patients with antibiotics, corticosteroids or cytostatics. There are no specific clinical symptoms for visceral candidiases or very little. It is necessary to think of barmy defeat of internal body when the disease accepts a long, sluggish current (pneumonia, enteritis, colitis, myocarditis, etc.), subfebrialny temperature is noted, there is no effect at usual methods of treatment, process at use of antibiotics worsens. Barmy damage of visible mucous membranes (especially visceral candidiasis of an oral cavity), nail rollers and nail plates which is often accompanied by damages of internals helps to suspect quite often. Less often in these cases various sites of an integument are surprised. Finally the issue is resolved on the basis of these laboratory researches.
Reasons of System candidiasis:
Express opinion that in a pathogeny of visceral candidiases the phenomenon of dysbacteriosis of which oppression under the influence of antibiotics of life activity of gram-negative sticks and cocci is characteristic matters, being in an organism of the healthy person antagonists of drozhzheiodobny mushrooms of the sort Candida and constraining their development. The greatest significance in development of dysbacteriosis is attached to antibiotics of a broad spectrum of activity (penicillin, streptomycin, synthomycin, etc.) and especially to their combinations. Use of antibiotics breaks vitamin balance in the patient's organism (for example, suppresses life activity of the colibacillus taking active part in synthesis and completion of various vitamins), there is a vitamin deficiency that promotes development of candidiasis. Consider that antibiotics directly stimulate development of drozhzheiodobny mushrooms. A certain part is assigned to corticosteroids and cytostatics though the mechanism of their action leading to candidiasis is studied insufficiently. Apparently, in a pathogeny of visceral candidiases the sorted reasons with dominance in one cases of a factor of dysbacteriosis, in others - a vitamin deficiency, etc. matter.
Treatment of System candidiasis:
Treatment of candidiasis of internals comes down to treatment of the background disease which became the reason of so expressed immunodeficiency against the background of reception of anti-mycotic drugs.
The forecast at candidosis defeats depends on firmness of immunity, but sepsis at children's age is, as a rule, a lethal outcome. After recovery mushrooms remain in an organism for the rest of life.
Prevention of system candidiasis consists in identification and timely treatment of local forms of candidiasis, elimination of the reasons of their emergence.