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Leyner's disease


Erythrosis desquamative Leynera-Moussa - a special type of an erythrosis at children of the first 3 months of the life which is followed by a generalized lymphadenopathy, diarrhea, a body weight increase delay.

Leyner etiologies:

The etiology of a desquamative erythrosis Leynera (erythroderma desquamatica neonatorum Lelner) is not finalized. There are several points of view on the reasons leading to development of a desquamative erythrosis. So, Leyner believed that the disease is caused by an endointoxication as he observed a constant combination of damages of skin to gastrointestinal frustration. Others consider that the disease is caused by an autoserotherapy to metabolism products, hypovitaminoses (a lack of biotin and vitamin A) the pathological course (toxicosis) of pregnancy. The disease proceeds hard and can end letalno, Use at treatment of children of antibiotics and vitamins improves the forecast.

Symptoms of a disease of Leyner:

The disease develops in the first months of life of the newborn at a hyponutrient in the form of the generalized eczematoid rashes coming from the area of generative organs, buttocks or a pilar part of the head. The diffusion erythematic and squamous edematous centers of defeat which are a little acting over level probably of not affected skin are characteristic. In the field of big folds can be moknuty, maceration, a macrolaminar peeling, on a pilar part of the head — seborrheal type fat scales. The disease develops against the background of dyspepsia, heavy enteritis, diarrhea of putrefactive character, an astekization, a hypotrophy (a lack of vitamin N of milk), hypochromia anemia, exudative diathesis, sometimes pneumonias. A hyperadenosis, a liver, spleens, a leukopenia, a gipoglobulinemiya are often observed.

Leyner's erythrosis proceeds with a normal temperature or subfebrile condition. Temperature increase to 38 — 39 °C is promoted by accession of complications. Reduction of number of eosinophils in blood or even their absence contrary to exudative diathesis and children's seborrheal eczema at which are, as a rule, noted an eosinophilia is characteristic.

Differential diagnosis of a desquamative erythrosis is carried out with seborrheal eczema, a syphilitic pemphigus, exfoliative dermatitis of Ritterr, candidiasis, an acute epidemic pemphigus of newborns which, as well as the syphilitic pemphigus, is excluded on the basis of positive takes of bakterioskopichesky researches and existence of violent elements. The positive symptom of Nikolsky and the beginning of rashes from face skin, around a mouth are characteristic of exfoliative dermatitis of Ritter.

At the children having seborrheal eczema, the general state, as a rule, remains good, there are no phenomena of enteritis, diarrhea, hypochromia anemia, the eosinophilia, uncharacteristic for Leyner's erythrosis comes to light.

Treatment of a disease of Leyner:

Administration of vitamins A, B2, B6, B12, folic acid, With, N. Vitamin N (biotin) is appointed on 0,003 — 0,005 g by 3 times a day. It is reasonable to carry out a hematotherapy, gamma-globulin injections. Antibiotics, and in hard cases — corticosteroids, anabolic hormones have favorable effect. The balanced diet, timely introduction of a feeding up are necessary. Hygienic care of the child provides purpose of the general heat baths (37,5 — 38 °C) with potassium permanganate or broth of oak bark, a train within 20 min., greasing by corticosteroid ointments, cream with vitamin A, 5% of Naphthalanum, 3 — 5% of sodium of borate.

Forecast. Now timely and rational treatment of a desquamative erythrosis of Leyner, a feeding schedule, hygienic leaving provide treatment of the child within several weeks.

Drugs, drugs, tablets for treatment of the Disease of Leyner:

  • Препарат Фокорт-Дарница.


    Corticosteroids for use in dermatology. Triamcinolonum.

    CJSC Pharmaceutical Firm Darnitsa Ukraine

  • Сайт детского здоровья