Lorizan

General characteristics. Structure:

Acting veshchestvo:loratadine;

1 gel contains a loratadin in terms of 100% substance of 5 mg;

auxiliary a veshchestva:karbomer 934P (карбопол 934P), glycerin, propylene glycol, ammonia solution of 15%, ethanol of 96%, formaldehyde solution, the water purified.

Pharmacological properties:

Antigistaminnyypreparat for topical administration. Has antiallergenic, anti-exudative and antipruritic properties. The main active ingredient of gel is лоратадин, H1 selectively blocking - histamine receptors. Drug has local antiallergic effect, reduces puffiness of a mucous membrane of a nose, exudation, an itch, recovers passability of a nose, facilitates breath. Has no sedative effect, does not cause accustoming.

Quickly, in 30 min. after use, eliminates symptoms of an allergy and works during 24 h. At topical administration drug has practically no systemic action.

Indications to use:

Prevention and treatment seasonal and chronic allergic rhinitises, vasculomotor rhinitis (a symptomatic treatment at a nose congestion, sneezing, allocations from a nose, an itch and dacryagogue); rinosinusita.

Route of administration and doses:

Nasal gel for topical administration.

To adults and children 2 years are more senior than Lorizan®nanosyat on a mucous membrane of a nose 2 times a day (if necessary - 3-4 times a day).

Treatment spend to achievement of therapeutic effect (on average from 2 to 5 days).

Features of use:

Administration of drug should be stopped for 48 h before conducting skin tests.

It is necessary to avoid hit of gel on a mucous membrane of eyes.

Side effects:

Лоризан®, as a rule, it is well transferred by patients. But emergence of feeling of an itch, dryness to a vort, disorders of digestive tract are sometimes possible increase in number of allocations from a nose.

Interaction with other medicines:

Medicinal interaction at topical administration of Lorizana®ne it is established. Along with it it is necessary to consider that Cimetidinum, erythromycin and кетоконазол increase concentration of a loratadin in blood. Loratadin reduces also erythromycin level in plasma by 15%. Does not exponentiate diazepam sedation. At simultaneous use of Lorizan®ne exponentiates the oppressing action on TsNS of ethanol and tranquilizers.

Contraindications:

The increased individual sensitivity to drug components, pregnancy, the feeding period a breast, children's age up to 2 years.

Use during pregnancy or feeding by a breast. Contraindicated.

Ability to influence speed of response at control of motor transport or work with other mechanisms. It is possible to appoint drug the patient performing the work requiring attention as it does not influence psychomotor functions, mental and mental capacities.

Children. It is contraindicated to apply to children under 2 years.

Overdose:

At a local route of administration danger of overdose is minimum.

Storage conditions:

Period of validity 4 years. To store in original packaging, at a temperature from 10 ºС to 20 ºС. To store in the place, unavailable to children.

Issue conditions:

Without recipe

Packaging:

On 15 g in a tuba. 1 tuba in a pack.