Топамакс
Application instruction:
Топамакс (the international name - Topiramat) treats group of anticonvulsants which block sodium receptors, stop
nervous excitement and remove spasms. Drug is effective for treatment of an epileptic syndrome, migraine, toniko-clonic attacks and Lennox-Gasto's syndrome.
Structure and form of release
The main active ingredient – топирамат 15-50 mg.
Auxiliary components: sucrose, starch, povidone, cellulose acetate, gelatin.
Топамакс is issued in capsules on 15, 25 and 50 mg placed in cardboard packaging on 28-60 pieces.
Pharmacological action of Topamaks
Топамакс is the effective antiepileptic drug increasing activity of GAMK-receptors and normalizing action of AMPK-receptors. Drug is used for treatment of epilepsy at an initial stage, migraine and spasmodic conditions of various etiology.
Топамакс has spasolytic, analgetic and antiinflammatory effect.
Received good comments of Topamaks as drug for bystry elimination of convulsive activity and removal of nervous irritability.
During treatment to the patients managing vehicles and engaged in activity on dangerous objects, it is necessary to be careful. Топамакс reduces the speed of psychomotor reactions.
Indications to use
Топамакс it is appointed for treatment of epilepsy, toniko-clonic attacks, migraine, Lennox's syndrome - Gasto, absentias epileptica, myoclonic and partial attacks.
Has positive reviews of Topamaks as auxiliary medicine for elimination of spasms of smooth muscles of muscles.
Topamaks's analogs
Topamaks's analogs are Maksitopir, Topalepsin, Topsaver, Toreal and Epimaks. These drugs have similar pharmacological effect, and they are effective for treatment of epilepsy, both in monotherapy, and in complex therapy.
Application instruction of Topamaks
According to the instruction, Topamaks at epileptic attacks it is necessary to accept inside 200 mg 2 times a day. If necessary it is possible to mix capsule contents with a small amount of water.
Adult patients can accept Topamaks together with other anticonvulsant drugs. The correct dosage has to be established by the attending physician.
At an initial stage of epilepsy of Topamaks it is necessary to begin to accept from 25 mg a day and to gradually increase a dosage. Increase in a dosage depends on clinical testimonies of the patient.
According to the instruction of Topamaks children cannot appoint up to 2 years, and from 2 to 10 years the dosage should not exceed 50 mg a day. Patients with diseases of kidneys have to have the minimum dosage.
As additional antiepileptic 
tool of Topamaks it is necessary to accept 9 mg 2 times a day. The course of treatment lasts 7 days.
Топамакс at migraine appoint to accept 100 mg 2 times a day. At strong attacks of migraine the dosage raises to 200 mg 2 times a day. For prevention the patient has to accept drug within 1 week on 25 mg of 1 times a day (before going to bed).
Contraindications
Contraindications to Topamaks's appointment are hypersensitivity and intolerance of components of drug, pregnancy and the period of breastfeeding, children's age up to 2 years, a liver failure, a serious illness of a brain, heart failure, malignant tumors.
With care drug is appointed at a nefrourolitiaza, a renal failure, osteoporosis and at advanced age.
Side effects of Topamaks
Топамакс can cause the following side effects:
- from system of digestion – diarrhea, vomiting, nausea, loss of weight, a loss of appetite;
- from the central nervous system – confusion of consciousness, a headache, dizziness, drowsiness, increased fatigue, a depression, hallucinations, uneasiness;
- from sense bodys – decrease in sight, a myopia, a hyperemia of a mucous membrane of eyes, a mydriasis, increase in intraocular pressure;
- allergic reactions – urticaria, an itch, an inflammation of mucous membranes, a Quincke's edema, dermatitis.
Name of drug
Price
Drugstore
Топамакс капс 25 mg No. 60, Janssen Pharmaceutica
1939 rub.
Network of the Moscow drugstores of IFCТопамакс капс 50 mg No. 60, Janssen Pharmaceutica
2743 rub.
Network of the Moscow drugstores of IFCWhen lovers kiss, each of them loses 6,4 calories a minute, but at the same time they exchange nearly 300 species of various bacteria.
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