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medicalmeds.eu Medicines H1 - antihistamines. Allergostop

Allergostop

Препарат Аллергостоп. SC Balkan Pharmaceuticals SRL (Балкан Фармасьютикалс) Республика Молдова


Producer: SC Balkan Pharmaceuticals SRL (Balkans Pharmasyyutikals) Republic of Moldova

Code of automatic telephone exchange: D04AA09, R06AC03

Release form: Firm dosage forms. Tablets.

Indications to use: Small tortoiseshell. Allergic rhinitis (cold). Allergic conjunctivitis. Pollinosis. Quincke's disease of Quincke. Serum disease. Medicinal allergy. Eczema. Contact dermatitis. Neurodermatitis. Skin itch. Toksikodermiya. Bronchial asthma. Intestinal infections.


General characteristics. Structure:

Active ingredient: 25 mg of Chloropyraminum in 1 tablet.

The drug rendering antiallergic, antihistaminic, cholinolytic, sedative, somnolent, spasmolytic action.




Pharmacological properties:

Pharmacodynamics. Blocks histamine H1 receptors and m-holinoretseptory. Weakens spazmogenny action of a histamine on smooth muscles of bronchial tubes and intestines, reduces its hypotensive effect and influence on permeability of vessels. Prevents development and facilitates the course of allergic reactions of immediate type. Has antipruritic, sedative and somnolent effect. Has moderate peripheral cholinolytic and spasmolytic activity.

Pharmacokinetics. At intake it is completely and quickly soaked up. Concentration in blood reaches a maximum during 2 h and remains at the therapeutic level for 4–6 h. It is evenly distributed in an organism, gets through GEB. It is metabolized in a liver, removed by kidneys and intestines.


Indications to use:

Allergic diseases (urticaria, rhinitis, conjunctivitis, pollinosis, Quincke's disease, serum disease), a medicamentous allergy, skin diseases (eczema, contact dermatitis, neurodermatitis, a skin itch, a toksikodermiya), initial stages of bronchial asthma of an easy current (as a part of complex therapy), acute respiratory diseases and intestinal infections at children (in combination with antipyretics).


Route of administration and doses:

Inside, during food, in oil and in / century.

Adults: on 25 mg 3–4 times a day (to 150 mg/days); in oil, in/in — 1–2 ml of 2% of solution.

Children: 2–3 times a day, 1–12 months on 6,25 mg, 1–6 years on 8,33 mg, 7–14 years on 12,5 mg.


Features of use:

Use at pregnancy and feeding by a breast. Contraindicated. For the period of treatment it is necessary to stop breastfeeding.

At acute allergic and anaphylactic reactions treatment is begun with in/in introductions, then passed to in oil. At use for children strict medical control is necessary (possibly hypersensitivity manifestation).

In an initial stage of therapy driving of vehicles and occupation is forbidden by the activity demanding bystry mental and motor reaction. It is necessary to exclude the use of alcoholic drinks during treatment.


Side effects:

From a nervous system and sense bodys: slackness, weakness, delay of psychomotor reactions, drowsiness, dizziness, incoordination of movements.

From bodies of a GIT: dryness in a mouth, nausea, gastrointestinal frustration; seldom — a gastralgia.


Interaction with other medicines:

The means alkalinizing urine raise, and acidifying — weaken therapeutic and side effects. Increases risk of development of spasms against the background of analeptics.

Strengthens action of narcotic analgetics, the general and local anesthetics, hypnotic drugs and sedatives, alcohol.

Tricyclic antidepressants promote manifestation of m - cholinolytic effects and the oppressing action on TsNS.

Barbiturates can accelerate metabolism and weaken effects.

The depriving of bonuses action on TsNS goes down caffeine and Phenaminum, amplifies — clonidine.


Contraindications:

Hypersensitivity, including to other derivatives of ethylene diamine, closed-angle glaucoma, prostate adenoma with the expressed disturbance of urodynamic, pregnancy, feeding by a breast, early chest age (up to 1 month).

Restrictions to use. Exacerbation of erosive and ulcer gastrointestinal diseases, urination delay.


Overdose:

Symptoms: adults have a block, a depression, disturbance of consciousness up to a coma, spasms are possible psychomotor excitement, it is rare — a hyperemia, a hyperthermia. Children have a mydriasis, a hyperemia and a hyperthermia, concern, excitement, hallucinations, an ataxy, an athetosis, spasms, a collapse, a coma.

Treatment: a gastric lavage, purpose of absorbent carbon, salt laxatives, maintenance of activity of cordial and respiratory system, if necessary — anticonvulsant therapy, IVL.


Storage conditions:

To store at a temperature of 15-25 °C, in dry, protected from light and the place, unavailable to children. Period of validity 3 years. Not to use after the expiry date specified on packaging.


Issue conditions:

According to the recipe


Packaging:

Tablets on 25 mg, 20 tablets in each blister, on one, two or three blisters together with the application instruction in cardboard packaging.



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